EXplaining PLasticity after stroke - EXPLORE-stroke:

eids Universitair Medisch Centrum0 个研究点目标入组 100 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

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•regarding the primary objective: 1) an upper limb deficit, i.e. a NIHSS score of 1-4 in the second week post stroke; 2) a first-ever ischemic lesion in the territory of the MCA, verified by CT and/or MRI scan; 3) age between 40 and 75 years; 3) written or oral informed consent; 4) be able to sit for 30 seconds without support. Regarding the secondary objective: patients > 1 year post stroke with a motor deficit of the upper extremity NHSS *1; healthy volunteers within expected age range of stroke survivors, i.e. 40-75 years.

•1) a pacemaker or other metallic implants; 2) upper extremity orthopaedic limitations; 3) not being able to communicate i.e. < 4 points on the
•Utrecht Communication Observation; 4) a Mini Mental State Examination, MMSE score of 22 points or less and 5) successful recombinant tissue plasminogen activator (rTPA, or alteplase) treatment.

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