Lung Scintigraphy for Pulmonary Embolism Diagnosis in COVID-19 Patients: a Multicenter Observational Study.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 183
- 试验地点
- 2
- 主要终点
- PE diagnosis on lung scintigraphy without the ventilation scan.
研究概览
简要总结
A frequent complication of COVID-19 disease is pulmonary embolism (PE).
Lung ventilation/perfusion (V/P) scintigraphy is a well-established test for PE diagnosis. The test is interpreted based on the recognition of wedge shaped perfusion mismatched defects. However, the ventilation procedure increases the potential risk of contamination by the aerosol secretion and the expired air.
A variety of strategies have been proposed in the nuclear medicine literature regarding performance of lung ventilation scintigraphy in COVID-19 patients with suspected acute PE. However, there is currently no factual data in this specific population to support recommendations to the nuclear medicine community.
The aim of this study was to assess the role of ventilation imaging when performing lung scintigraphy for suspected PE in COVID-19 patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with suspected COVID-19 disease
- •Referred for lung scintigraphy for suspected acute PE
排除标准
- •Patient under guardianship or curatorship
- •Patient deprived of liberty by an administrative or judicial decision
- •Inability or refuse to give consent
结局指标
主要结局
PE diagnosis on lung scintigraphy without the ventilation scan.
时间窗: 1 day
Percentage of scans for which the diagnostic conclusion of the lung scan would have been different when omitting the ventilation scan
次要结局
未报告次要终点