Spirulina Supplementation In Recovery From Damaging Exercise
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Measure changes in the concentration of blood plasma inflammatory markers via immunoassay.
研究概览
简要总结
Exercise can cause muscle damage, leading to a loss in muscle function, increased muscle soreness and inflammation. Evidence supports the use of nutritional strategies to help recovery. Spirulina is a type of algae. It is eaten as a food supplement as it is full of micronutrients, some which provide anti-inflammatory benefits. This work will assess the impact of taking spirulina supplements on recovery from hard exercise. Investigators will measure changes in muscle function, soreness and markers of inflammation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Are available and willing to attend St Luke's Campus, Exeter
- •Age 18 - 40
- •BMI 18.5 - 30 kg/m2
- •The participant exercises / plays sport for > 2 h/week, but doesn't do structured resistance strength training
- •Self-reported as healthy (absence of injury or disease)
- •Have no known food allergy to algae
- •Are not taking any over the counter or prescribed medication that might interfere with study, e.g. anti-inflammatory medication
- •Non-smoker
排除标准
- •Are unable to attend St Luke's Campus, Exeter
- •Are out-with age range 18 - 40
- •BMI below 18.5 or above 30 kg/m2
- •The participant does not exercise
- •The participant does regular structured resistance strength training
- •Known injury or disease that might influence study outcomes
- •Have a known food allergy to algae
- •Are taking over the counter or prescribed medication that might interfere with study, e.g. anti-inflammatory medication
结局指标
主要结局
Measure changes in the concentration of blood plasma inflammatory markers via immunoassay.
时间窗: Measurements take place across a 6 day experimental period.
Blood plasma inflammatory markers will be measured before (baseline) and after eccentric exercise (at 3, 6, 24, 48 and 72 h post eccentric exercise) in both the spirulina and placebo group. Inflammatory markers that will be assessed include: interferon γ (IFN-γ), interleukin (IL) -1β, -4, -6, -10, tumour necrosis factor α (TNF-α) via immunoassay (pg/mL).
次要结局
- Measure changes in muscle function of the quadriceps using knee extensor total isokinetic work on a Biodex System 3 isokinetic dynamometer.(Measurements take place across a 6 day experimental period.)
- Measure changes in muscle function of the quadriceps using knee extensor peak isometric torque on a Biodex System 3 isokinetic dynamometer.(Measurements take place across a 6 day experimental period.)
- Measure changes in perceived lower body muscle soreness via visual analogue scale questionnaire.(Measurements take place across a 6 day experimental period.)