Comparison of Anti-plaque Efficacy of Natural Honey With Chlorhexidine Mouthwash: A Randomized Controlled Trial
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Dental Plaque
研究概览
简要总结
The rationale of our study is to compare the efficacy of natural honey base preparation with other commercially available mouthwashes i.e chlorhexidine base in prevention of dental plaque formation as honey is readily available and cost effective and organic in nature. This study will help to provide the data of our community and positive result may provide a new method of oral hygiene maintenance with fewer side effects. We will be able to deliver the best anti-plaque agent.
详细描述
In this study, participants will assigned into 2 group those who will fulfilled the inclusion and exclusion criteria. After the informed consent, they were divided into 2 group. Group A will received Chlorhexidine mouthwash and Group B will provided with honey based mouthwash. The participant will blinded as solution will be provided in dark color bottle to mask the study. After which the baseline plaque index will be taken followed by recording plaque index on 7th, 14th, and 21st day. The statistical analysis will be done to compare the mean difference between these 2 groups
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
盲法说明
The mouthwash were distributed in dark color coded bottle and marked with label A and B, as to maintain masking among the the participants of the study.
入排标准
- 年龄范围
- 18 Years 至 25 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Individual aged between 18-25
- •Retained 28 number of teeth excluding wisdom teeth
排除标准
- •Individual with medical illness affecting oral cavity like diabetes, sjögren syndrome, crohn disease etc
- •Multiple extraction , overhang restoration, wearing any appliance
- •Periodontal problem with pocket depth more than 3mm
- •Current or recent history of antibiotic consumption
- •Noncompliance that is unable to maintain their hygiene.
- •Pan, Betel quid and any other oral habit will not be included in study
研究组 & 干预措施
Chlorhexidine
these are the group which received chlorhexidine based preparation for plaque reduction
干预措施: Chlorhexidine mouthwash (Drug)
Natural honey
these group will received the honey base mouthwash and the its effect on plaque reduction will be observed in follow up visits
干预措施: Natural honey (Other)
结局指标
主要结局
Dental Plaque
时间窗: reduction of plaque index will be assessed on 7th day, 14th day and on 21st day
primary outcome is to assessed the reduction on plaque level among Group A and Group B
次要结局
未报告次要终点
研究者
Muhammd Abid
Registrar at LCMD
Liaquat National Hospital & Medical College