NCT06002750已完成不适用
The Third People's Hospital of Hangzhou
The Third People's Hospital of Hangzhou1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2021年11月24日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- the Tp-e interval and Tp-e/QT ratio were positively correlated with Inflammation.
研究概览
简要总结
The goal of this observational study is to investigate ventricular repolarization utilizing Tp-e intervals and Tp-e/QT ratios in patients with DM. The main questions it aims to answer are:
- 1.Exploring the changes in ventricular repolarization parameters (QT interval, QTc interval, QTd, Tp-e interval, Tp-e/QT ratio) in patients with dermatomyositis, providing quantifiable indicators for early detection of arrhythmia in dermatomyositis patients;
- 2.Exploring the role of inflammation in ventricular repolarization in DM patients, providing a basis for in-depth research on the diagnosis and prevention of arrhythmia in DM patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Regardless of gender, registered residence and education level, voluntarily participate in this study and sign the informed consent form.
- •Clinical diagnosis of Dermatomyositis.
排除标准
- •Previous history of heart disease (such as myocardial infarction, cardiac pacing, congenital heart disease, ischemic heart disease, etc.), chronic kidney disease, etc; Patients with other connective tissue diseases; Pregnant and lactating women.
- •Taking drugs that affect electrocardiogram indicators, such as macrolides, quinolones, quinidine, amiodarone, antipsychotic drugs, etc.
- •Patients with severe lack of case data.
结局指标
主要结局
the Tp-e interval and Tp-e/QT ratio were positively correlated with Inflammation.
时间窗: November 2011 to November 2022
QTc, Tp-e interval, and Tp-e/QT ratio were increased in DM patients.
时间窗: November 2011 to November 2022
次要结局
未报告次要终点
研究者
Ling Pin
Chief physician
The Third People's Hospital of Hangzhou
研究点 (1)
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