TO STUDY ACUTE KIDNEY INJURY IN NEONATES ADMITTED IN NEONATAL INTENSIVE CARE CENTRE : A CROSS SECTIONAL STUDY
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- To minimise the potential risk of harm to neonates and assess the immediate outcome of patients
研究概览
简要总结
All newborns’ taking part in the study, written informed consent will be taken from their parents /guardians in a language they can understand. All newborns admitted in NICU will make up the study group .Detailed history taking , complete physical examination and investigation will be done.
All cases enrolled in the study will be subjected to the following Detailed maternal history like gravida , peripartum infections, history of drug in take during pregnancy, foul smelling liquor , Detailed history taking, Detailed General and Physical examination to be done , Investigations ( Complete Blood Count, Serum Electrolytes, Kidney function test , Urine routine and microscopy , C-reactive protein , Blood culture , Fractional excretion of sodium FENa )
Therefore, Kidney function test (KFT) will be done in newborn at 48 hrs of life and will be repeated after 24 hrs to see the S. Creatinine level and assess the stage of AKI .
If newborn is > 2 days then kidney function test will be done at the time of admission and will be repeated after 24 hrs.
Imaging – Ultrasound of whole abdomen and Computed tomography if required.
Therefore, KDIGO Classification will be used to define and stage AKI.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 0.00 Day(s) 至 28.00 Day(s)（—）
- 性别
- All
入选标准
- •Neonates whose parents gave consent.
- •Neonates who are admitted in NICU.
排除标准
- •Antenatally diagnosed renal congenital anomaly and preterm neonates less than 24weeks.
结局指标
主要结局
To minimise the potential risk of harm to neonates and assess the immediate outcome of patients
时间窗: Day 0 , 2 and 3
次要结局
- Classify the type of AKI (prerenal or renal or postrenal ) and to assess the immediate outcome of patients.
研究者
Dr Divya Agarwal
Rohilkhand medical college and hospital