JPRN-UMIN000020239已完成未知
Effects of Dapagliflozin on Body Weight in Japanese Patients with Type 2 Diabetes Mellitus. SUMS-ADDIT-2 - Effects of Dapagliflozin on Body Weight in Japanese Patients with Type 2 Diabetes Mellitus. SUMS-ADDIT-2 (Shiga University of Medical Science Anti-Diabetic Drugs Intervention Study-2)
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 52
研究概览
简要总结
The change in BM was significantly larger in the Dapa than in the Con group, with a difference in the mean change of-1.72 kg (95 %CI: -2.85, -0.59; P = 0.004) between the groups. IHTG content was significantly reduced in the Dapa than in the Con (P = 0.033). Changes in AAs showed small differences between the groups, but only serine concentrations were significantly reduced in the Dapa.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 75years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1) History of receiving a SGLT-2 inhibitor 2) Receiving insulin or GLP-1 agonist 3) With severe ketosis, diabetic coma, or precoma 4) Contraindication to the use of dapagliflozin (history of hypersensitivity to dapagliflozin, or pregnant, etc.) 5) History of hospitalization for infection, trauma, or surgery within 6 months 6) History or under treatment of brain infarction, transient ischemic attack 7) With an episode of angina pectoris or myocardial infarction within 6 months 8) Receiving loop diuretics 9) With orthostatic hypotension 10) Considered inadequate by the investigator
研究者
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