Can Insecticide-treated School Uniforms Reduce Dengue Infections in School-aged Children in Thailand
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 1,825
- 试验地点
- 1
- 主要终点
- insecticide:placebo incidence rate-ratio (per 1,000 person-years) of laboratory-confirmed dengue cases in school-aged children
研究概览
简要总结
This is a randomised controlled trial that will be conducted in eastern Thailand in a group of schools with approximately 2,000 students aged 7-15 years. Pre-fabricated school uniforms will be commercially treated to ensure consistent high quality of insecticide impregnation with permethrin. A double-blind randomised cross-over trial at the school level will cover two dengue transmission seasons.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 7 Years 至 15 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •pupils in participating schools
排除标准
- •skin sensitivity, exema
结局指标
主要结局
insecticide:placebo incidence rate-ratio (per 1,000 person-years) of laboratory-confirmed dengue cases in school-aged children
时间窗: up to 2 years
Schools are cross-over randomised to insecticide-treated or untreated (placebo) school uniforms, and so the primary outcome is the rate-ratio of dengue fever cases in school children, compared between these two groups.
次要结局
- comparison between intervention and placebo groups of number of serious skin reactions to insecticide-treated uniforms(up to 2 years)
研究者
Peter Byass
Professor of Global Health
Umeå University