NCT04601818已完成不适用
Planned Semi-Elective Lung Transplantation Using 10C Cold Static Preservation: A Proof-Of-Concept Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- Incidence of ISHLT Primary Graft Dysfunction Grade 3 at 72 hours (expected rate less than 20%)
研究概览
简要总结
When suitable donor lungs become available for a consented recipient, and the donor cross clamp time occurs between 6pm and 4am, the transplant procedure (anesthesia starting time) will be allowed to be moved to a 6am start or later with the lungs being preserved at 10C cold static preservation upon organ arrival to our hospital using a specific refrigerator. The maximum allowed time between donor cross clamp and recipient anesthesia initiation will be 12h.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Primary lung transplantation
- •Informed consent provided
- •Donor Inclusion: Age<70
排除标准
- •Re-transplantation
- •Multi-organ transplantation
- •Donor exclusion criteria:
- •Age >70y
- •Concerns with organ preservation technique
结局指标
主要结局
Incidence of ISHLT Primary Graft Dysfunction Grade 3 at 72 hours (expected rate less than 20%)
时间窗: 72 hours post op
次要结局
- 1-year survival(procedure up to 1 year post op)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Planned Semi-Elective Lung Tx StudyLung TransplantationNCT04616365University Health Network, Toronto70
已完成
不适用
Planned Semi-Elective Lung Transplantation Using 10C Cold Static PreservationPulmonary DiseaseNCT04568694NYU Langone Health1
招募中
不适用
DREAM: Double Lung Transplant REgistry Aimed for Lung-limited MalignanciesBilateral CancerLung TransplantLung CancerNCT05671887Northwestern University125
Unknown
不适用
Empowerment of Lung and Heart-lung Transplant PatientsLung TransplantationHeart-Lung Transplantation"Rehabilitation"PsychotherapyExercise TrainingNCT00808600Hannover Medical School132
招募中
不适用
Optimization of Donor-Recipient Matching in Lung TransplantationLung TransplantNCT05195853Fondation Hôpital Saint-Joseph500