Effect of Physical Activity an Stress in Children
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Change in salivary Cortisol and maximal levels of salivary cortisol in response to the TSST stress test over 2 hours
研究概览
简要总结
The objective of the study is to evaluate the impact of physical activity in obese and nonobese prepubertal children on:
- biological stress responses during a psychosocial stress test
- snacking and feeling of hunger in response to the same psychosocial stress test
- the moderating factor of attachment on the biological stress responses and on snacking
Children will be investigated on one study day during 3.5 hours.
详细描述
Hypotheses In this study, 3 primary hypotheses will be tested.
- Moderate physical activity during 25 min in children decreases the cortisol levels in response to the Trier Social Stress Test TSST-C (for children).
- Moderate physical activity during 25 min in children decreases the snacking (calorie consumption when corrected for expenditure and switch in quality of food intake) in response to the Trier Social Stress Test TSST-C (for children).
- A secure attachment will be a moderating factor for the general increase in cortisol and the snacking in response to the psychosocial stress test (Trier Social Stress Test TSST-C).
Secondary objectives:
- To test if the impact of physical activity on stress responses and snacking differs between obese and non-obese children
- To test the impact of physical activity on the cardiovascular stress reactivity (blood pressure, heart rate) and the perceived stress (scale) in response to the Trier Social Stress Test TSST-C?
- To test if the stress reactivity and its modulation by physical activity is different in anxious and in impulsives/labile children
- To test if serious life events and parental worries and parental educational style influence the stress reactivity
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 7 Years 至 10 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •7-10 year old children
排除标准
- •Severe illness
- •Medications interfering with study
结局指标
主要结局
Change in salivary Cortisol and maximal levels of salivary cortisol in response to the TSST stress test over 2 hours
时间窗: 9 months
Snacking (Caloric intake, corrected for energy expenditure)
时间窗: 9 months
Measure of caloric intake and measure of choice of high-caloric vs low-caloric food snacking after the TSST stress test
Moderator effect of attachment (4 different attachment categories), i.e. children with a secure attachment will have lower rises in cortisol compared with children in the other 3 attachment categories
时间窗: 9 months
Cortisol levels after the TSST stress test will be lower in children with secure attachment compared to detached, disorganized or preoccupied children (i.e. the 3 other attachment categories).
次要结局
- Cardiovascular reactivity (changes and maximal levels of blood pressure, heart rate)(9 months)
- Perceived stress (stress scale from 1-7)(9 months)
- Moderator effect of obesity (WHO criteria)(9 months)
- Moderator role of serious life events and parental worries(9 months)
研究者
Jardena Puder
Medin adjoint
University of Lausanne Hospitals