A Randomised controlled trial to Evaluate the effectiveness and cost benefit of prescribing high dose FLuoride toothpaste in preventing and treating dEntal Caries in high-risk older adulTs

Manchester University NHS Foundation Trust0 个研究点目标入组 1,161 人开始时间: 2017年6月2日最近更新: 2022年8月15日

适应症

试验速览

2019 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/31126270 protocol (added 29/05/2019)

•Current inclusion criteria as of 15/07/2022:
•1. Patients attending dental practices participating in the trial
•2. Aged 50 years or older
•3. Diagnosis of active coronal caries (into dentine) in the last 12 months which may/may not have been treated, or any root caries; and\or other risk factors as determined by their GDP
•4. Living in any residential setting
•5. Receive their dental care in part or fully as an NHS patient
•6. Patients whose GDP decides prescription of high concentration fluoride toothpaste is appropriate
•Previous inclusion criteria:
•1. Patients attending dental practices participating in the trial
•2. Aged 50 years of age or older
•3. Diagnosis of active coronal caries (into dentine) in the last 12 months which may/may not have been treated, or any root caries; and\or other risk factors as determined by their GDP
•4. Living in any residential setting

•Current exclusion criteria as of 15/07/2022:
•1. Currently prescribed (by GDP or GP) high concentration fluoride toothpaste (for GDPs, prescription must have been issued at last examination visit)
•2. Unable to provide informed consent
•3. Hypersensitivity for sodium fluoride and/or other ingredients used in 5000ppm toothpaste
•4. Are living in the same household as someone already recruited to REFLECT, or someone who is routinely using a high concentration fluoride toothpaste
•Previous exclusion criteria:
•1. Currently prescribed high concentration fluoride toothpaste
•2. Unable to provide informed consent

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