Effects of Landscapes on the Brain: Assessment of Neurophysiological Response in Healthy and Depressed Individuals to Different Landscape Quality Exposures in Singapore
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 95
- 试验地点
- 2
- 主要终点
- EEG power in alpha band
研究概览
简要总结
There is an established consensus between researchers that the contact with natural environments has beneficial influence on mental health and well-being of people exposed to them. The knowledge in this area is based mostly on the correlational analyses, but more research is needed to explore the causal relationships between the human and his environment. More specifically, in order to identify specific restorative mechanisms in response to the specific types and components of the designed landscapes, especially in the highly urbanized context.
This study will attempt to find the psychophysiological responses in human brain to landscapes videos (in the lab), and real landscapes with different visual quality, carefully pre-selected and analysed in terms of landscape composition. In the study the rigorous experimental protocol will be administered in order to acquire qualitative and quantitative data both self-reported and measured by neuroscience tools, in order to demonstrate the causal effect of landscape exposure on the brain activity patterns and mood of healthy and depressed individuals.
详细描述
Understanding of the impact of urban green landscapes with different design and levels of contemplativeness on brain function may pave the way to more scientifically informed and more healthy planning and design of urban living environment.
Also the exposure to certain types of landscapes may be useful in mental health promotion and support for the existing treatments in patients with depression.
Specific aims The aim of the study is to assess the effects of passive exposure (viewing) images of differently designed landscapes on the brain activity of two groups: 1) healthy individuals and 2) patients with depression, using electroencephalography (EEG) and Functional Near-Infrared Spectroscopy (fNIRS). The investigators also want to compare effects of exposure to images with the in-situ immersion with the real environment.
Following the assumption that there are certain types and components of the living environments that influence our mental health and well-being even if one is passively exposed to them, the investigators want to to assess the effects of passive exposure to three differently designed, representative landscapes on the brain activity of healthy individuals. And to compare effects of exposure to images with the in-situ immersion with the real environment.
Hypothesis The investigators hypothesise that landscapes, that the Therapeutic Garden, which also achieved a high score in the Contemplative Landscape expert evaluation scale, will induce the brain activity patterns commonly associated with the relaxation, and bottom-up attention, unlike the other selected sites with lower scores. Additionally, the investigators hypothesize that in the real landscape exposures they will observe this phenomenon more intensely than in the case of images exposure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
盲法说明
participants do not know the hypothesis of a study, other people cannot influence the brainwave reaction
入排标准
- 年龄范围
- 21 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age of 21 to 75
- •Right-handed only
- •(They must suffer from depressive disorder)
排除标准
- •Major neurological disorders e.g. epilepsy, stroke
- •Any form of cancer
- •Major heart diseases: e.g. ischemic heart disease
- •Major lung diseases: e.g. chronic obstructive pulmonary disorder.
- •Major liver disease e.g. liver failure
- •Major kidney disease e.g. kidney failure.
结局指标
主要结局
EEG power in alpha band
时间窗: 5 minutes
predictor of positive affect and positive mental health outcomes, measured with EEG
fNIRS haemodynamics
时间窗: 5 minutes
decreased oxy-hemoglobin in the frontal part of the brain indicates more relaxation
EEG power in beta band
时间窗: 5 minutes
more beta in the right temporal lobes associated with stimuli-driven attention, measured with EEG
次要结局
- Profile of mood states(30 minutes)
- landscape preference measured with self-assessment manikin scale.(30 minutes)
研究者
Agnieszka Olszewska-Guizzo
Principal Investigator
National University of Singapore