Evaluation of Anesthetic Techniques in Outpatient Total Joint Replacement Surgery in an Integrated Health Care Delivery System
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12,466
- 试验地点
- 1
- 主要终点
- Postoperative Morbidity
研究概览
简要总结
The study is a retrospective cohort study of adult patients undergoing outpatient primary unilateral total knee or total hip replacement surgeries from 2017 to 2019 assessing for difference in anesthetic techniques and outcomes.
详细描述
The study is a retrospective cohort study of adult patients undergoing outpatient primary unilateral total knee or total hip replacement surgeries from 2017 to 2019. The purpose of the study is to evaluate the effects of anesthetic techniques for primary total joint replacement in Northern California Kaiser Permanente. The primary objective is to determine if there are clinically and statistically significant differences between the outcomes of general anesthesia and neuraxial anesthesia.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •ASA 1 - IV patients
- •Age > 18
- •Primary total hip/knee replacement
排除标准
- •Total joint replacement for oncologic tumors
- •Emergent surgery
- •Age < 17
- •Pregnant Female
- •Neuraxial anesthesia conversion to general anesthesia
- •Revision total joint replacement
- •Bilateral total joint replacement
结局指标
主要结局
Postoperative Morbidity
时间窗: 30-day postoperative
30-day Postoperative Morbidity including surgical site infection (defined as infection involving the skin or subcutaneous tissue of the incision, deep incisional infection defined as infected tissue below the subcutaneous tissue including fascia and muscle), major coronary events (defined as nonfatal myocardial infarction, heart failure, ventricular tachycardia, cardiac arrest), pneumonia, urinary tract infection, venous thromboembolism, pulmonary embolism, cerebrovascular accident, renal injury/failure (Defined as increase in baseline creatinine 2 fold/3fold respectively).
次要结局
- Postoperative opioid use(Day of surgery)
- Postoperative readmission(30-day postoperative)
- Postoperative Mortality(30-day postoperative)
- Intraoperative blood loss and transfusion rates(Day of surgery)
- Length of postsurgical hospital stay(Day of surgery)
- Intraoperative opioid use(Day of surgery)
- Postoperative Pain Scores(Day of surgery)
- Postoperative nausea and vomiting(Day of surgery)