跳至主要内容
临床试验/NCT06745830
NCT06745830招募中不适用

Lymph Node Pathologic Grading Strategy: Under the Backdrop of the IASLC Grading System for Invasive Lung Adenocarcinoma - a Retrospective Cohort Study

Fudan University1 个研究点 分布在 1 个国家目标入组 2,998 人开始时间: 2024年4月10日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
2,998
试验地点
1
主要终点
5-year RFS

研究概览

简要总结

The percentage of high-grade patterns in metastatic LNs (mLNs) that can predict poor outcomes has yet to be determined. Additionally, the potential implications of other histologic patterns in metastatic lymph nodes on patient outcomes warrant further investigation.

We conducted a retrospective cohort study to investigate the prognostic value of pathologic pattern in metastatic lymph nodes.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • From January 2011 to September 2021, we consecutively collected patients with invasive LUAD who underwent surgical resection at the Department of Thoracic Surgery, Fudan University Shanghai Cancer Center.

排除标准

  • adenocarcinoma in situ, minimally invasive adenocarcinoma, invasive mucinous adenocarcinoma, and other variants of adenocarcinoma;
  • incomplete common driver mutation data;
  • unavailable pathologic slides.

结局指标

主要结局

5-year RFS

时间窗: 5 years

次要结局

  • 5-year OS(5 years)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Haiquan Chen

Director in the Department of Thoracic Surgery, FUSCC

Fudan University

研究点 (1)

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