NL-OMON56047招募中不适用
ltrasound and magnetic resonance imaging to assess muscle contractile performance in FSHD. - Muscle+
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •All participants:
- •Age between 18 and 70 years.
- •Informed consent is given by the participant.
- •Ability to read and understand written and spoken instruction in Dutch.
- •Willingness and ability to understand nature and content of the study.
- •Patients with FSHD:
- •Clinically and genetically proven FSHD type 1 or type 2.
排除标准
- •A potential subject who meets any of the following criteria will be excluded
- •from participation in this study:
- •All participants:
- •BMI >= 35
- •Other diseases that could diffusely affect muscle integrity or disturb the
- •imaging appearance beyond that what can be extrapolated.
- •Wheelchair dependence.
- •Pregnancy
- •In stage 2: participants who will undergo an MRI-scan
- •-Any contra-indications for MRI, including:
- •o Claustrophobia
- •o Pacemakers and defibrillators
- •o Nerve stimulators
- •o Intracranial clips
- •o Intraorbital or intraocular metallic fragments
- •o Cochlear implants
- •o Ferromagnetic implants (e.g. thoracic implant for scoliosis)
- •o Inability to lie supine for 60 minutes
- •o Necessity of (continuous) daytime ventilation
- •o Scoliosis surgery
- •Healthy participants:
- •Any known nerve or muscle disorder affecting the muscles measured.
研究者
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