A comparative clinical trial to evaluate the effectiveness of Yavakshara and Vyoshadi guggulu in the management of Grade 11 Non Alcoholic Fatty Liver Disease NAFLD
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 26
- 试验地点
- 1
- 主要终点
- Changes in value of AST and ALT in LFT
研究概览
简要总结
A comparative clinical trial is planned in Grade 11 Non Alcoholic Fatty Liver (NAFLD) to compare yawith yavakshara and vyoshadi guggulu, will be done among 13 participants in each group of 45 days in the age group of 20-65 years. Participants selected concecutively as per inclusion criteria into two groups from the OPD of VPSV Ayurveda college Kottakkal. Group 1 will be managed with yavakshara capsule 500 mg, twice daily after food. Group 2 will be treated with vyoshadi guggulu 500 mg twice daily after food. Assesment will be done based on blood parameters like AST and ALT on 0th and 45 th day. No special diet modification /life style changes will be advised during this period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Diagnosed case of grade 11 fatty liver through usg Elavated AST and ALT ALT not greater than 5 times of AST.
排除标准
- •known case of malignancy unconytrolled DM, HTN Participants contraindicated for paneeyakshara.
结局指标
主要结局
Changes in value of AST and ALT in LFT
时间窗: 0th and 45th day
次要结局
未报告次要终点
研究者
Dr Fathima Nithusha
VPSV Ayurveda College kottakkal