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临床试验/NCT00128388
NCT00128388已完成2 期

Randomized Controlled Trial of Psychodynamic Psychotherapy vs. Applied Relaxation for Panic Disorder

Weill Medical College of Cornell University2 个研究点 分布在 1 个国家目标入组 49 人开始时间: 2000年2月最近更新:
适应症

试验速览

阶段
2 期
状态
已完成
入组人数
49
试验地点
2
主要终点
PDSS (panic disorder severity scale)

研究概览

简要总结

This study will determine the effectiveness of a manualized form of brief psychodynamic psychotherapy in comparison with applied relaxation training in treating adults with panic disorder.

详细描述

This is a randomized controlled trial of a manualized form of brief psychodynamic psychotherapy in comparison with applied relaxation training, a less active form of treatment in other studies, for adults with primary Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) panic disorder.

Forty nine patients who have signed written consent who have primary DSM-IV panic disorder have been entered into the study. Randomization has been stratified by presence of major depression and use of psychoactive, anti-panic medications. Medications, if present, have been held constant. All patients have received 24 sessions of either psychodynamic psychotherapy, or applied relaxation training for panic disorder. This study is currently closed for recruitment, although final follow-up assessments have yet to be completed.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 55 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • 18-55 years old
  • Primary DSM-IV panic disorder with or without agoraphobia
  • Severity 5/8 minimum on the Anxiety Disorders Interview Schedule

排除标准

  • Psychosis
  • Unstable medication dosage
  • Unwilling to discontinue ongoing psychotherapy
  • Organic mental syndrome
  • Substance use or abuse

结局指标

主要结局

PDSS (panic disorder severity scale)

时间窗: termination, 2, 4, 6, 12 month f/u

次要结局

  • SDS (Sheehan disability scale)(termination, 2, 4, 6, 12 month f/u)
  • HARS (Hamilton anxiety rating scale)(termination, 2, 4, 6, 12 month f/u)
  • HDRS (Hamilton depression rating scale)(termination, 2, 4, 6, 12 month f/u)

研究者

申办方类型
Other

研究点 (2)

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Psychodynamic Therapy for Treating Panic Disorder | 临床试验