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临床试验/NCT04991610
NCT04991610Unknown不适用

Sex Determination From Scapula Using 3-D Computed Tomography in Sample of Sohag Governorate Population

Sohag University1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2021年7月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
100
试验地点
1
主要终点
Maximum scapular length

研究概览

简要总结

One of the most difficult areas of forensic science is identifying individuals. Accurate sex estimation based on measurements of dimorphic dimensions in unknown human remains is a crucial first step toward making individual identification.

the most accurate approach to determine sex by bone size is based on os coxae or skull. After natural disaster their presence can never be guaranteed, therefore the development of methods of sex determination using other skeletal elements is crucial.

The scapula is a paired short bone that will be researched in this study. The decision to focus on the scapula was made in the first place because of its minor morphological alterations after growing is complete. Second, short and flat bones appear to be better maintained than lengthy bones, which are frequently fractured, scattered, and mixed together.

Scapular muscle attachments provide protection to the bone making it difficult to fracture or break .

Comparative studies on different populations have shown population-specific results in the discriminant function equations for sex estimation.

There is significant population variation due to sexual dimorphism in the growth rate and developmental process of human beings. Genetics play an important role in this variation. Nevertheless, environmental factors, nutrition, secular changes and diseases also play an important role in sexual dimorphism .

详细描述

One of the most difficult areas of forensic science is identifying individuals. Accurate sex estimation based on measurements of dimorphic dimensions in unknown human remains is a crucial first step toward making individual identification. the most accurate approach to determine sex by bone size is based on os coxae or skull. After natural disaster their presence can never be guaranteed, therefore the development of methods of sex determination using other skeletal elements is crucial.The scapula is a paired short bone that will be researched in this study. The decision to focus on the scapula was made in the first place because of its minor morphological alterations after growing is complete. Second, short and flat bones appear to be better maintained than lengthy bones, which are frequently fractured, scattered, and mixed together. Comparative studies on different populations have shown population-specific results in the discriminant function equations for sex estimation. There is significant population variation due to sexual dimorphism in the growth rate and developmental process of human beings. Genetics play an important role in this variation. Nevertheless, environmental factors, nutrition, secular changes and diseases also play an important role in sexual dimorphism. The first study that used the scapula in sex estimation was conducted by Dwight in 1894.

Dwight measured the height of the glenoid fossae and maximum scapular length of 123 patients (84 males and 39 females),Dwight's method showed that the scapular height had a high predictive value.

In 2010, Dabbs and Moore-Jansen applied the 23 parameter method to 803 individuals of the Hamann-Todd collection in their study and showed that the overall accuracy of this method was 95.7%.

studies reveal that the use of Computed tomography (CT) images increases accuracy and reproducibility over traditional methods in establishing a biological profile .

even though there is evidence of sexual dimorphism in the scapula according to several published studies, the validity of scapula for sex estimation has not been explored in depth in modern population where a general lack of contemporary osteometric databases noted.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
25 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • persons above 25 years old

排除标准

  • Cases below 25 years
  • scapular, vertebral fractures
  • growth disorders
  • severe osteoporosis
  • arthritis
  • previous orthopedic surgery
  • infection

结局指标

主要结局

Maximum scapular length

时间窗: 12 Months

the parameter measured The length between the highest point of superior angle and lowest point of inferior angle via software program . All CT scans will be obtained from patients lying in a supine position using 120 kV tube voltage, 150 effective mA and 1 mm slice thickness parameters.

Maximum length of spine

时间窗: 12 Months

the parameter measured From the medial border of the scapula at the spinous axis to the most lateral point on the scapular spine via software program . All CT scans will be obtained from patients lying in a supine position using 120 kV tube voltage, 150 effective mA and 1 mm slice thickness parameters.

Scapular breadth

时间窗: 12 Months

the parameter measured from the middle of the dorsal border of glenoid fossa to the end of spinal axis on the vertebral border. via software program All CT scans will be obtained from patients lying in a supine position using 120 kV tube voltage, 150 effective mA and 1 mm slice thickness parameters.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Daila Mohamed Khalaf

Teaching Assistant, Department of Forensic Medicine and Toxicology

Sohag University

研究点 (1)

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