Comparison the effects of memantine and sodium valproate in migraine pain prophylaxis

Ardabil University of Medical Sciences0 个研究点目标入组 80 人开始时间: 待定最近更新: 2019年1月29日

适应症

试验速览

暂无简介。

•A history of migraines based on the criteria of the international community of headache.
•The number of headache attacks is more than three attacks per month.
•Failure of prophylactic treatment with one or more migraine prevention drugs.
•Any headache attack with more than 48 hours of analgesia should be distinguished from other attacks
•Filling out the consent form of the Clinical trial
•age 16 to 65

•Other headache
•Use of other migraine prevention medications
•Drug dependence on drugs or alcohol
•Renal dysfunction
•Excessive use of acute migraine attack drugs (more than 8 days in the month of receiving ergots, NSAIDs or tryptans)
•Sensitization to memantine or sodium valproate or their compounds.
•Acute resistant migraine
•Severe psychiatric disorders (bipolar disorder, mental disorder, severe depressive disorder, obsessive-compulsive disorder, or functional disorder, general anxiety disorder, Somatization)
•Neurodegenerative disorders
•malignancy , pain disorder, severe infection
•Pregnant or Breastfeeding women

发起方