Discovering Novel Cancer Treatment Options Using a Comprehensive NGS-based Liquid Molecular Testing Panel in the Community Setting. ("DINOSAur II")
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 572
- 试验地点
- 1
- 主要终点
- European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30 (QLQ-C30)
研究概览
简要总结
To prospectively identify cancer patients whose tumors express specific molecular markers targeted by therapeutic agents from a comprehensive l i q u i d molecular test, for the purpose of selecting the most clinically appropriate treatment in a pragmatic two arm trial.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who have given informed consent in accordance with the methods and procedures of this study
- •Diagnosis of cancer (stage 3 and stage 4; solid tumors only) requiring medical care
- •Patients who have not received treatment related to his/her cancer
- •Patients who are willing to sign a release of medical records to the research team
- •Male and female patients ≥18 years of age
- •Patients under oncology care
- •Sufficient clinical status for collection of blood sample within usual care
排除标准
- •Patients considered minors in the jurisdiction where the protocol is conducted
- •Patients who are prisoners and pregnant women
- •Patients who cannot provide consent and did not sign a power of attorney
结局指标
主要结局
European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30 (QLQ-C30)
时间窗: 2 years
The EORTC Core Questionnaire (QLQ-C30) includes six clearly distinguishable functioning scales that have been thoroughly tested and validated on an international level and that are available in 110 different language versions. The scaling of items is 1 (Not at all) to 4 (Very much), 1 (Very poor) to 7 (Excellent). The higher the score the better the quality of life.
次要结局
- Compare the proportion of enrolling in clinical trials(2 years)
研究者
Mihran Shirinian
Principal Investigator
Glendale Adventist Medical Center d/b/a Adventist Health Glendale