CRI and Continuous Assessment of Hemodynamic Compensation to Guide Fluid and Pressor Management in Severely Ill Patients With COVID-19
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- Number of Patients with Acute Kidney Injury (AKI)
研究概览
简要总结
The FDA has approved the CipherOx CRI T1 Tablet for use in subjects aged 19-36, and that this study aims to evaluate the device in subjects aged outside of this range and is being used off label.
The FDA determined the Cipher OX CRI T1 Tablet to be a class II device in 2016, and additional research has been done since the FDA determination to further support the use of the device outside of its current labeling.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Eligible patients will be those who are:
- •COVID-19 positive;
- •Ages > 18 and < 70 years old;
- •Require > 2 liters of oxygen by nasal cannula to maintain SpO2 > 90%;
- •Are admitted to the sixth floor at University Hospital, on one of two designated Hospitalist services (approximately 16 COVID-19 positive patients/service).
排除标准
- •COVID-19 negative
- •Age <18 or >70 years
- •On <2 liters oxygen via nasal canula
- •Incarcerated
- •Decisionally Challenged
结局指标
主要结局
Number of Patients with Acute Kidney Injury (AKI)
时间窗: 1 year
Number of patients who acquire an acute kidney injury
FiO2 needs
时间窗: 1 year
FiO2 levels administered
mortality
时间窗: 1 year
Number of patients who experience mortality
Volume of IV fluid infused
时间窗: 1 year
Volume of IV fluid infused during treatment
Days on Oxygen
时间窗: 1 year
Days spent on oxygen
Quantity of Blood pressure medication administered
时间窗: 1 year
Amount of blood pressure medication utilized during treatment
Resuscitation status
时间窗: 1 year
Categorical determination of resuscitation status as over- or under- resuscitated
Number of participants with hospital acquired pneumonia
时间窗: 1 year
Number of participants with hospital acquired pneumonia
Number of patients with hemodynamic collapse
时间窗: 1 year
Number of patients who experience hemodynamic collapse defined as drop in systolic blood pressure below 80mm Hg
次要结局
未报告次要终点