Comparison of Clinical Effect Between Endoscopic and Microscopic Ear Surgery of Cholesteatoma: A Multicenter Retrospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 186
- 主要终点
- Pure Tone Average(PTA)
研究概览
简要总结
Background: Cholesteatoma is a potentially life-threatening inflammatory lesion that causes hearing loss, ear discharge, and ear pain, and serious complications. For the past several decades, most studies of cholesteatoma have been restricted to microscopic ear surgery. However, a growing body of evidence suggests endoscopic ear surgery is a safe, minimally invasive approach for cholesteatoma management. This thesis aim to investigate and compare the clinical effect between endoscopic and microscopic ear surgery of cholesteatoma.
Materials and methods: The retrospective study included 186 patients with cholesteatoma who received endoscopic or microscopic ear surgery from 11 otorhinolaryngology centers between November 2016 and March 2021. Patients were followed-up for at least 1 year. Audiometry improvement, treatment cost, time, graft success rate and recurrence rate were assessed after surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 6 Years 至 80 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •postoperative pathologically were confirmed cholesteatoma with or without mastoid involvement
- •the extent of disease was confirmed by preoperative HRCT temporal bone
- •undergoed microscopic and/or endoscopic surgery for cholesteatoma including primary or revision surgery
排除标准
- •were lacking in clinical characteristics
- •had not preoperative audiometric data
- •missed the follow-up data
- •were lacking in surgical times
- •were microscopic combined endoscopic ear surgery
结局指标
主要结局
Pure Tone Average(PTA)
时间窗: at least 1 year
estimate the auditory acuity
Air-Bone Gap(A-B Gap)
时间窗: at least 1 year
estimate the auditory acuity
次要结局
未报告次要终点