Effects of Downhill Walking in Pulmonary Rehabilitation for Patients With Idiopathic Pulmonary Fibrosis
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 34
- 试验地点
- 1
- 主要终点
- 6 Minutes Walking Distance (6MWD)
研究概览
简要总结
In this study; will examine the effects of downhill walking (eccentric exercise training) on exercise capacity, quality of life, and blood lactate levels in individuals with IPF. After the initial assessment, patients will be randomized into two groups: downhill walking PR group and Standard PR Group.
详细描述
Individuals diagnosed with idiopathic pulmonary fibrosis who come to the Pulmonary Rehabilitation Unit of Istanbul Süreyyapaşa Chest Diseases and Chest Surgery Education and Research Hospital will be included in this study. Those who meet the inclusion criteria will be randomized into two groups: Downhill Walking Pr Group (n=17) and Standard Pr Group (n=17). Patients will have exercise sessions twice a week for 8 weeks. Patients will be evaluated immediately before the rehabilitation program and the end of 8 weeks exercise programme. In our study, downhill walking training will differ from traditional walking training only in terms of treadmill training protocol. Traditional walking training involves walking on a motorized treadmill with a neutral incline, progressing with increases in speed, while downhill walking training will be performed at a constant -10% incline.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Having a diagnosis of IPF according to the clinical diagnostic criteria of the American Thoracic Society and/or the European Respiratory Society (ATS-ERS).
- •Being between the ages of 18 and
- •Being able to walk on a treadmill.
- •Having the ability to cooperate.
- •No change in current medication in the last month.
- •Not participating in a structured activity program for at least six months.
- •Accepting the purpose and method of this study voluntarily and give informed consent for the study.
排除标准
- •Presence of physical or mental impairment that prevents informed consent or compliance with the protocol.
- •Inability to attend more than 20% of pulmonary rehabilitation sessions.
- •Presence of major cardiovascular disease (coronary artery disease, uncontrolled hypertension, arrhythmias, or heart failure).
- •Presence of existing orthopedic and neuromuscular exercise limitations.
- •Acute exacerbation
研究组 & 干预措施
Downhill Walking PR Group
A standard pulmonary rehabilitation (PR) exercise program will be implemented. Downhill treadmill walking will be included during walking sessions.
干预措施: Pulmonary Rehabilitation (Other)
Downhill Walking PR Group
A standard pulmonary rehabilitation (PR) exercise program will be implemented. Downhill treadmill walking will be included during walking sessions.
干预措施: Downhill Walking (Other)
Standard PR group
A standard pulmonary rehabilitation (PR) exercise program will be implemented. Walking will be performed on a treadmill without incline.
干预措施: Pulmonary Rehabilitation (Other)
Standard PR group
A standard pulmonary rehabilitation (PR) exercise program will be implemented. Walking will be performed on a treadmill without incline.
干预措施: Treadmill Walking without incline (Other)
结局指标
主要结局
6 Minutes Walking Distance (6MWD)
时间窗: Baseline and the end of the 8 weeks exercise program
6 MWD means the distance the patient walked in 6 minute walk test. Its unit is meters.
Saint George Quality of life questionnaire
时间窗: Baseline and the end of the 8 weeks exercise program
The St. George's Respiratory Questionnaire (SGRQ) is designed to measure quality of life. Four scores are calculated Symptoms, Activity, Impacts, and Total. Saint George Respiratory Questionaire (SGRQ) score: The SGRQ ranges from 0 (no impairment of quality of life) to 100 (highest impairment of quality of life).
次要结局
- Peripheral muscle strength(Baseline and the end of the 8 weeks exercise program)
- Fatigue severity scale(Baseline and the end of the 8 weeks exercise program)
- Spirometric measurements (First second forced expiratory volume)(Baseline and the end of the 8 weeks exercise program)
- Spirometric measurements (FEV1/FVC ratio)(Baseline and the end of the 8 weeks exercise program)
- Spirometric measurements (Forced vital capacity)(Baseline and the end of the 8 weeks exercise program)
- Hand grip strength(Baseline and the end of the 8 weeks exercise program)
- Modified Medical Research Council Dyspnea Score(Baseline and the end of the 8 weeks exercise program)
- Hospital anxiety depression scale (HADS)(Baseline and the end of the 8 weeks exercise program)
- Determination of blood lactate level(Baseline and the end of the 8 weeks exercise program)
- Carbon monoxide diffusion capacity(Baseline and the end of the 8 weeks exercise program)
研究者
ESRA PEHLIVAN
Associate Professor
Saglik Bilimleri Universitesi