Modes of Ventilation During Laparoscopic Bariatric Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Change in heart rate
研究概览
简要总结
During minimally invasive surgery, a pneumoperitoneum is created to facilitate surgical visualization. Although effective in facilitating the procedure, there are respiratory consequences of the pneumoperitoneum, which significantly increases intra-abdominal pressure (IAP) up to 20 cmH2O. The increased IAP can decrease functional residual capacity and increase closing capacity resulting in increased resistance, decreased compliance, and increased ventilation-perfusion mismatch. In a randomized, cross-over design, this study will evaluate in sequential order, 3 modes of ventilation during laparoscopic bariatric surgery to determine which is better able to support oxygenation and ventilation while limiting the peak inflating pressure (PIP).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 14 Years 至 20 Years(Child, Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Laparoscopic bariatric surgery requiring intra-arterial blood pressure monitoring, age 14-20 years.
排除标准
- 未提供
结局指标
主要结局
Change in heart rate
时间窗: Baseline to 30 mins.
Heart rate will be assessed every 5 mins. during each 30 minute mode of ventilation.
次要结局
- Change in blood pressure(Baseline to 30 mins.)
- Blood gas(30 mins.)
研究者
Joseph D. Tobias
Chairman - Dept. of Anesthesiology & Pain Medicine
Nationwide Children's Hospital
