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临床试验/NCT04203654
NCT04203654Unknown不适用

Implementation and Effectiveness of Multidiscipline-Integrated Addiction Treatment Model

National Health Research Institutes, Taiwan2 个研究点 分布在 1 个国家目标入组 48 人开始时间: 2020年2月24日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
48
试验地点
2
主要终点
Urine amphetamine test During Intervention

研究概览

简要总结

Management of substance use disorders in clinical settings is challenging. Approaches with integrated bio-psycho-social interventions, along with the engagement of families and self-help groups are strongly recommended. The Matrix intensive outpatient program has been developed in UCLA to help the psychostimulant misusers in the Southern California in 1980's. With integration of the existing evidence of addiction researches and empirically supported cognitive-behavior treatment techniques, the Matrix model developed manuals to address knowledge and skills needed for drug users in their early recovery and relapse prevention. The treatment was delivered in a 16-week intensive structured group sessions. There was also a 12-week educational sessions for the in-treatment individuals and their families. A substantial body of evidence has demonstrated the successful experience of the Matrix treatment model in management a broad spectrum of addictive disorders in many countries.

The objectives of the pilot project are to set up a multi-center collaborative clinical network with implementation of an integrated addiction treatment program modified from the UCLA Matrix model. Via the establishment of standardized subject recruitment criteria, treatment and outcome assessment procedures, the study aims to assess the adherence of participating clinical organizations to the study protocol, the acceptance of participating MA misusers for the integrated treatment program as well as the outcomes and their determinants for the treatment models.

详细描述

Methamphetamine (MA) use disorder is a serious legal and health problem worldwide. Reports from Ministry of Justice in Taiwan revealed that the MA-related crimes has tremendously increased over the past decade. The arrested users of scheduled II drugs, MA mainly, has surged from 34,886 in 2014 to 54,190 in 2016 in Taiwan. It is critical to tackle the emerging problems in Taiwan.

Management of MA use disorder in clinical settings is challenging. Approaches with integrated bio-psycho-social interventions, along with the engagement of families and self-help groups are strongly recommended. The Matrix intensive outpatient program has been developed in UCLA to help the psychostimulant misusers in the Southern California in 1980's.With integration of the existing evidence of addiction researches and empirically supported cognitive-behavior treatment techniques, the Matrix model developed manuals to address knowledge and skills needed for drug users in their early recovery and relapse prevention. The treatment was delivered in a 16-week intensive structured group sessions. There was also a 12-week educational sessions for the in-treatment individuals and their families. A substantial body of evidence has demonstrated the successful experience of the Matrix treatment model in management a broad spectrum of addictive disorders in many countries.

The objectives of the pilot project are to set up a multi-center collaborative clinical network with implementation of an integrated addiction treatment program modified from the UCLA Matrix model. Via the establishment of standardized subject recruitment criteria, treatment and outcome assessment procedures, the study aims to assess the adherence of participating clinical organizations to the study protocol, the acceptance of participating MA misusers for the integrated treatment program as well as the outcomes and their determinants for the treatment models.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
20 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Aged 20-65
  • Current methamphetamine use disorder by DSM-5, moderate and above
  • Willing and able to provide informed consents

排除标准

  • Severe physical or psychiatric conditions requiring emergent treatment
  • Currently involved in judicial or criminal conditions
  • Plan to go abroad or relocate in the next 6 months

结局指标

主要结局

Urine amphetamine test During Intervention

时间窗: 16 weeks

This test looks for amphetamine in urine once a week for 16 weeks.

Urine amphetamine test,Follow-Up

时间窗: 3 months

This test looks for amphetamine in urine once a month for 3 months.

次要结局

  • The World Health Organization Quality of Life -BREF (WHOQOL-BREF) During Intervention(16 weeks)
  • The World Health Organization Quality of Life -BREF (WHOQOL-BREF),Follow-Up(3 months)

研究者

发起方
National Health Research Institutes, Taiwan
申办方类型
Other
责任方
Sponsor

研究点 (2)

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