A Cross-Sectional Study on Bilateral Asymmetry of Respiratory Muscle Activity During Breathing in Children With Spastic Cerebral Palsy: Surface Electromyography Analysis
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Root Mean Square (RMS) of Respiratory Muscle Activity
研究概览
简要总结
This observational cross-sectional study investigates the bilateral asymmetry of respiratory muscle activity during breathing in children with spastic cerebral palsy (CP). Children with CP often exhibit structural deformities, which may lead to impaired chest mobility and asymmetric respiratory function. The primary objective is to objectively evaluate the imbalance in the activation of bilateral respiratory muscles (intercostal, external oblique, and sternocleidomastoid) using non-invasive surface electromyography (sEMG). Muscle activity will be measured during resting breathing and active breathing tasks. The findings aim to provide clinical evidence for developing selective respiratory muscle training programs for this population.
详细描述
Children with spastic cerebral palsy frequently experience abnormal muscle tone and motor control issues, leading to structural deformities like scoliosis and pelvic asymmetry. These structural changes can restrict chest wall mobility and cause inefficient, asymmetrical breathing patterns. While ultrasound is often used to assess diaphragm function, it has limitations in evaluating functional respiratory pressure differences based on gross motor function levels and requires high cognitive cooperation. Therefore, this study utilizes surface electromyography (sEMG) to quantify the muscle activation (Root Mean Square, RMS) of respiratory and accessory muscles. The study involves children aged 4 to 12 years with spastic CP. Measurements are conducted in a seated position under two main conditions: 30 seconds of resting breathing and an active breathing task involving blowing a pinwheel or bubbles. An Asymmetry Index (AI) will be calculated to compare the degree of bilateral muscle activation imbalance across the different breathing conditions.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 4 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children with Gross Motor Function Classification System (GMFCS) Level I or II
- •Children with sufficient cognitive ability to understand instructions and voluntarily perform tasks
- •Children with a Trunk Appearance Clinical Evaluation (TRACE) score of 4 or higher out of a total of 12 points
排除标准
- •Children who have undergone orthopedic surgery of the spine or lower extremities, or received botulinum toxin injection treatment within the past 6 months
- •Children with acute or chronic respiratory diseases, such as asthma or acute pneumonia
- •Children with severe cardiac disorders, intellectual disabilities, or visual and auditory impairments that may interfere with the experiment
研究组 & 干预措施
Spastic Cerebral Palsy Group
Children aged 4 to 12 years with spastic cerebral palsy, GMFCS level I-II, and TRACE score of 4 or higher.
干预措施: Surface Electromyography (sEMG) assessment (Diagnostic Test)
结局指标
主要结局
Root Mean Square (RMS) of Respiratory Muscle Activity
时间窗: Up to 30 minutes (measured once during the single-day assessment session)
Muscle activation amplitude of the intercostal, external oblique, and sternocleidomastoid muscles measured using surface electromyography (sEMG). The raw sEMG signals are full-wave rectified and smoothed using a 50ms moving window to calculate the RMS values during resting and active breathing tasks.
Asymmetry Index (AI) of Respiratory Muscle Activation
时间窗: Up to 30 minutes (measured once during the single-day assessment session)
The asymmetry index will be calculated using the Root Mean Square (RMS) values obtained from surface electromyography (sEMG) . The formula used is (Right RMS - Left RMS) / (Right RMS + Left RMS) X 100 . The index evaluates the percentage of imbalance between the right and left respiratory muscles (intercostal, external oblique, and sternocleidomastoid) during resting breathing and active breathing tasks.
次要结局
未报告次要终点
研究者
Yoo jemin
Graduate Student
Sahmyook University