Pilot Intervention for PTSD, Nonadherence, and HIV Risk
试验速览
- 阶段
- 不适用
- 入组人数
- 70
- 试验地点
- 2
- 主要终点
- PTSD symptoms
研究概览
简要总结
The primary aim of this project is to examine the efficacy of prolonged exposure (PE) therapy at reducing HIV-related PTSD symptoms, increasing adherence to antiretroviral medication regimens, and increasing health-related quality of life (QOL) in HIV+ patients.
详细描述
HIV+ patients will be randomized to receive either PE therapy (up to 18 possible sessions) or weekly symptom monitoring (described below) and will complete measures of PTSD, adherence, and QOL pre- and post-intervention and at 3- and 6-month follow-up assessments. Secondary analyses will examine the impact of the intervention on disorders commonly comorbid with PTSD (i.e., anxiety, mood, and substance abuse/dependence disorders).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Must be HIV+
- •Must meet PTSD diagnostic criteria
- •Must be taking HIV medications
- •Must be able to read and write in English
排除标准
- •Current or previous diagnosis of schizophrenia, any current diagnosis with psychotic features, or current suicidal ideation
- •Being in a current abusive relationship or ongoing intimate relationship with one's assailant
- •Mental retardation
研究组 & 干预措施
1
Prolonged Exposure Therapy.
干预措施: Prolonged Exposure Therapy (Behavioral)
2
Weekly monitoring/Waitlist Control Group.
结局指标
主要结局
PTSD symptoms
时间窗: pre- & post-intervention, 3-month post, & 6-month post
次要结局
- Adherence to HIV medications(pre- & post-intervention, 3-month post, & 6-month post)
- Health-related Quality of Life(pre- & post-intervention, 3-month post, & 6-month post)