NCT01595945终止不适用
Effect of Caloric Restriction and Gastric Bypass on Resting Metabolic Rate in Obese Subjects
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 75
- 试验地点
- 4
- 主要终点
- Resting metabolic rate
研究概览
简要总结
Studies in overweight and obese subjects show a decline in resting metabolic rate (RMR) even after moderate caloric restriction. Yet the onset and course of such a metabolic adaption is still unclear. Lower resting metabolic rates were also reported after gastric banding bariatric surgery but have not yet been investigated in subjects after gastric bypass. The purpose of this study is to investigate the consequences on resting metabolic rate in subjects with obesity after moderate caloric restriction or gastric bypass.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •BMI ≥30 kg/m2
排除标准
- •Marked weight reduction in the last 2 years (>5% of initial body weight)
- •Recent extreme fasting (during the last month)
- •Manifest eating disorders (assignment to a specialist for eating disorders)
- •Severe psychiatric disorders requiring treatment
- •Pregnancy, lactation
结局指标
主要结局
Resting metabolic rate
时间窗: 24 weeks
次要结局
- Body Mass Index(24 weeks)
- Caloric restriction(24 weeks)
- Weight loss(24 weeks)
- Body composition (muscle mass, fat mass)(24 weeks)
研究者
研究点 (4)
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