NCT01881802Unknown不适用
Study of Opioid Immunosuppressive Effects
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 主要终点
- real-time quantitative polymerase chain reaction
研究概览
简要总结
This trial aims to investigate the effects of opioid-inducing immune suppression on opioid drug abused patients. The methods of the investigators research mainly includes the expression of morphine-related miRNAs in peripheral blood mononuclear cells and cytokine in plasma.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •subjects were excluded if they had a chronic systemic illness (cardiac, renal, pulmonary, hepatic, endocrine, metabolic, or autoimmune disorders) or
- •a major psychiatric disorder or
- •if they were abusing substances other than heroin (as determined by urine drug test result). For women, pregnancy was also a reason for exclusion.
排除标准
- •Control subjects with no history of drug or alcohol abuse were also excluded if they had
- •major medical or psychiatric disorders
结局指标
主要结局
real-time quantitative polymerase chain reaction
时间窗: up to 2 months
次要结局
- enzyme-linked immuno sorbent assay(up to 2 months)
研究者
Xiaohong Long
doctoral candidate
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
相似试验
已完成
2 期
Investigation of Naltrexone for Pathological GamblingPathological GamblingNCT01057862Yale University9
已完成
不适用
μ-opioid Receptor Polymorphism and Opioid AnalgesiaPharmacogenetic and Duration of Labor Fentanyl AnalgesiaNCT02099877American University of Beirut Medical Center250
已完成
1 期
St. PETERsburg Pain and Alcohol Intervention With Naltrexone and NalmefeneHIV InfectionAlcohol UsePainNCT03278886Boston Medical Center11
已完成
不适用
Effect of Ibuprofen on Postoperative Opiate Medication Use and Shoulder Functional OutcomesRotator Cuff Tear ArthropathyNCT02588027University of California, San Francisco110
已完成
1 期
Opioid Antagonism in Individuals Ascertained Through the Partners HealthCare BiobankReproductive DisordersNCT04975347Stephanie B. Seminara, MD47