Correlation Between Cardiac Output and Recovery Time After Reversal of Rocuronium-Induced Blockade With Sugammadex
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- Mayo Clinic
- 入组人数
- 7
- 试验地点
- 1
- 主要终点
- Recovery Time After Administration of Sugammadex and Its Correlation to Cardiac Output Measure
研究概览
简要总结
The purpose of this research is to determine the time it takes to reverse the effects of the intraoperative medication given to relax the muscles and how this period of recovery correlates with a function of the heart.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age > or = 18 years old.
- •Patients willing to participate and provide an informed consent.
- •Patients undergoing an elective surgical procedure requiring administration of rocuronium, and the use of a pulmonary artery catheter intraoperatively.
排除标准
- •Patients with unilateral disorders, such as stroke, carpal tunnel syndrome, broken wrist with nerve damage, Dupuytren contracture.
- •Patients with systemic neuromuscular diseases such as myasthenia gravis.
- •Patients with significant organ dysfunction that can significantly affect pharmacokinetics of neuromuscular blocking and reversal agents, i.e., severe renal impairment or end-stage liver disease.
- •Patients having surgery that would involve prepping the arm or leg into the sterile field.
研究组 & 干预措施
TetraGraph monitoring
Subject scheduled to undergo an elective surgical procedure will have TetraGraph device lead placement on either hand at a discretion of the anesthesiologist
干预措施: TetraGraph (Device)
结局指标
主要结局
Recovery Time After Administration of Sugammadex and Its Correlation to Cardiac Output Measure
时间窗: Up to 1 hour postoperative
The correlation between the mean change in cardiac output measurement after reversal with sugammadex to the time it takes to recover from the rocuronium-induced blockade. The Pearson's correlation method was used to calculate the correlation coefficient.
次要结局
- Correlation of Speed of Recovery From Neuromuscular Blockade and Age.(Up to 1 hour postoperative)
研究者
J. Ross Renew, M.D.
Principal Investigator
Mayo Clinic