ITMCTR1900002547尚未招募1 期
Clinical study for the characteristics of nasal and intestinal microflora and the effect of probiotic intervention in people with high exposure to PM2.5
The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine0 个研究点开始时间: 待定最近更新:
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional study
入排标准
- 年龄范围
- 22 至 65（—）
- 性别
- All
入选标准
- •Inclusion criteria of high exposure population:
- •(1) Sanitation workers and traffic guides working in traffic pollution environment in Chengdu, age: 22 to 65 years old, male and female are not limited, fixed post working years >= 3 years, fixed place working time >= 8 hours;
- •(2) there was no history of gastroenteritis in the past month;
- •(3) no hormones and antibiotics were used in the past month;
- •(4) no nasal spray or other probiotics (such as lactic acid bacteria, bifidobacterium, etc.) yoghurt and beverage were used in the past 3 months;
- •(5) clinical examination of lip, throat, ear, nostril (especially anterior nostril) and neck, no lymph node enlargement, inflammation, polyp, mass, runny nose, etc;
- •(6) no chronic constipation (defecation < 3 times a week) and hemorrhoids.
- •Inclusion criteria of low exposure population:
- •(1) the staff of Chengdu Urban Environmental Hygiene Administration Bureau working indoors and the staff of Chengdu Traffic Administration Bureau working indoors (with air conditioning), age: 22 to 65 years old, male and female; Fixed post working years >= 3 years, fixed place working time >= 8 hours;
- •(2) there was no history of gastroenteritis in the past month;
- •(3) no hormones and antibiotics were used in the past month;
- •(4) no nasal spray or other probiotics (such as lactic acid bacteria, bifidobacterium, etc.) yoghurt and beverage were used in the past 3 months;
- •(5) clinical examination of lip, throat, ear, nostril and neck (especially anterior nostril), no lymph node enlargement, inflammation, polyp, mass, runny nose, etc;
- •(6) no chronic constipation (defecation < 3 times a week) and hemorrhoids.
排除标准
- •(1) patients with a history of gastrointestinal surgery;
- •(2) patients with a long history of drug use;
- •(3) a history of smoking;
- •(4) pregnancy and lactation;
- •(5) those who could not understand and cooperate with the experimental process;
- •(6) patients who had participated in other clinical trials in the past 1 month.
研究者
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