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临床试验/NCT06529133
NCT06529133已完成不适用

The Effect of Dual Task on Postural Control in Children Diagnosed with Epilepsy

Bezmialem Vakif University2 个研究点 分布在 2 个国家目标入组 30 人开始时间: 2024年7月26日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
30
试验地点
2
主要终点
Evaluation of postural control under two conditions

研究概览

简要总结

An individual's postural control is often accompanied by other tasks in daily life, such as cognitive tasks. Cognitive dual task (cognitive dual task) is the ability to perform two or more cognitive and motor activities simultaneously. There are studies in the literature that address the postural control of different patient populations and healthy individuals while performing a cognitive task. To our knowledge, there is no study evaluating the postural control skills of children with epilepsy during a cognitive dual task using dynamic posturography (Biodex). In this respect, it is possible to say that our study constitutes the first study that can contribute to the literature on this subject.

详细描述

Epilepsy is often characterized by seizures, but may also include additional neurological signs and symptoms that affect the prognosis of the disease. These clinical findings include hypotonia, athetosis, ataxia, inadequate visual-motor functioning, gait abnormalities, balance disorders and learning disabilities. In the literature, it has been reported that individuals with epilepsy who use antiepileptic drugs have more balance problems than those who do not. It is also reported that people with epilepsy exercise less than the general population and have a lower level of functionality compared to their peers. It has also been reported that there is a relationship between age at onset of epilepsy and motor problems.

Executive functions include cognitive processes that support complex, goal-directed behavior, especially in novel situations or situations that require conscious effort. In children diagnosed with epilepsy, visuospatial skills are frequently affected within the scope of executive function.

Postural control mechanism is a complex neural function consisting of the integrated function of sensory input, motor output and modulation by cerebellar and cognitive influences. Lack of coordination and postural instability, motor limitations in patients with epilepsy, and disabilities due to seizures are complaints due to side effects of antiepileptics. Inadequate postural control, which involves the orientation of the body for stabilization in space or task-oriented orientation in harmony with the environment, limits the individual's ability to adapt to the environment or unexpected situations.

An individual's postural control is often accompanied by other tasks in daily life, such as cognitive tasks. Cognitive dual task (cognitive dual task) is the ability to perform two or more cognitive and motor activities simultaneously. There are studies in the literature that address the postural control of different patient populations and healthy individuals while performing a cognitive task. To our knowledge, there is no study evaluating the postural control skills of children with epilepsy during a cognitive dual task using dynamic posturography (Biodex). In this respect, it is possible to say that our study constitutes the first study that can contribute to the literature on this subject.

15 children who are followed up with a diagnosis of epilepsy at Istanbul Faculty of Medicine Child Neurology Polyclinic and who meet the inclusion criteria will be included in the study as the study group, and 15 healthy children in the same age group will be included in the study as the control group. Informed consent will be obtained from each child and parent and the study will be conducted in accordance with the Declaration of Helsinki.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Single Group
主要目的
Screening
盲法
None

入排标准

年龄范围
7 Years 至 16 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Being between the ages of 7-16
  • Having been diagnosed with epilepsy
  • Having had a seizure in the last 2 years
  • Being on antiepileptic medication
  • Having a body mass index within normal limits (18.5-24.9 kg/m2)

排除标准

  • Being hypermobile (Beighton score >5 and above)
  • Leg length inequality
  • Having any neurological, rheumatic, musculoskeletal, metabolic and connective tissue disease
  • Pain, deformity or surgical history related to the vertebral column and lower extremity
  • Presence of cognitive, mental and/or serious psychiatric disease
  • Participating in any exercise program or sporting activity in the last six months
  • Hearing and/or vision loss
  • For the control group:
  • Inclusion Criteria:
  • Being between the ages of 7-16
  • Having a body mass index within normal limits (18.5-24.9 kg/m2)
  • Exclusion Criteria:
  • Being hypermobile (Beighton score >5 and above)
  • Leg length inequality
  • Having any neurological, rheumatic, musculoskeletal, metabolic and connective tissue disease
  • Pain, deformity or surgical history related to the vertebral column and lower extremity
  • Presence of cognitive, mental and/or serious psychiatric disease
  • Participating in any exercise program or sporting activity in the last six months
  • Hearing and/or vision loss

结局指标

主要结局

Evaluation of postural control under two conditions

时间窗: Day 1

Postural control abilities of the children will be evaluated with Biodex Balance System (BBS). Half an hour later, the same tests will be repeated during the cognitive dual task.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Deniz Tuncer

Assistant professor

Bezmialem Vakif University

研究点 (2)

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