临床试验/NCT04322786

NCT04322786Unknown不适用

The Use of Angiotensin Converting Enzyme Inhibitors and Incident Respiratory Infections, Are They Harmful or Protective? An Analysis Using UK Based Electronic Health Records of 5.6 Million Individuals.

University College, London0 个研究点目标入组 1,302,508 人开始时间: 1998年1月1日最近更新: 2020年11月13日

适应症

干预措施

试验速览

阶段: 不适用
发起方: University College, London
入组人数: 1,302,508
主要终点: Incidence of influenza

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者记录与标识符相似试验

研究概览

简要总结

The study use UK based linked electronic health records from the Clinical Research Datalink (CALIBER) of 5.6 million individuals to conduct a matched case-control study to investigate the incidence of influenza in individuals prescribed ACEI compared to those not prescribed ACEI.

研究设计

研究类型: Observational
观察模型: Case Control
时间视角: Prospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•We identify individuals aged 18 years or older and registered in the current primary care practice for at least one year.

排除标准

•We exclude individuals with a prior history of influenza and viral pneumonia before study entry.

研究组 & 干预措施

ACEI user

Individuals with an ACEI prescription in the study population.

干预措施: ACE inhibitor (Drug)

结局指标

主要结局

Incidence of influenza

时间窗: Jan 1st 1998 - May 31st 2016

次要结局

未报告次要终点

研究者

发起方

University College, London

申办方类型

Other

责任方

Sponsor

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