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临床试验/CTRI/2024/07/070854
CTRI/2024/07/070854尚未招募不适用

Comparison of hand sensibility and nerve conduction in individuals with and without neurodynamic response of upper limb

Harshika Raut1 个研究点 分布在 1 个国家目标入组 134 人开始时间: 2024年8月3日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
134
试验地点
1
主要终点
Elbow extension angle in degrees in Upper limb neurodynamic test (ULNT 1) , Hand Sensibility Measures includes Vibration Threshold in Volts,

研究概览

简要总结

An altered upper limb neurodynamic testing (ULNT 1) and abnormal nerve conduction serve as early indicators of peripheral neural dysfunctions that may aid in detecting unknown subclinical pathology in healthy adult individual.  Also altered sensibility may also suggest change in sensory nerve fibers but there is dearth in study comparing the sensory nerve conduction velocity in individuals with and without altered neurodynamic tension. Therefore study aims to compare hand sensibility measures, including Vibration Threshold, Two-point Discrimination, Monofilament testing, and nerve conduction, in asymptomatic individuals with altered responses to upper limb neurodynamic testing.The study begins with the screening of asymptomatic healthy individuals approached through advertisement flyers distributed at various locations. Written informed consent will be obtained from participants before performing ULNT, after which participants will be categorized into the study or comparison group based on the response to ULNT . Subsequently, hand sensibility measures such as vibration threshold using a bioesthesiometer, two-point discrimination using a Disk-criminator, light touch using monofilament testing, and nerve conduction amplitude and velocity using a Sensory nerve conduction machine will be measured.

The study will continue until January 2025. Data obtained will be analyzed using Jamovi 2.3.28.

研究设计

研究类型
Observational

入排标准

年龄范围
20.00 Year(s) 至 45.00 Year(s)(—)
性别
All

入选标准

  • Study Group: Participants presenting responses like pain, tingling, and numbness before 30 degrees of end-range elbow extension while performing upper limb neurodynamic test -1 (ULNT-1) sequence.
  • Comparison Group: Participants without any response or response at terminal range of elbow extension while performing ULNT-1 sequence.

排除标准

  • Previous history of upper limb / cervical neural symptoms of pain or dysfunction for last 3 months.
  • Known case of diabetes, thoracic outlet syndrome, brachial plexus injury, spinal cord injury, spinal disorders, cancer, tumors.

结局指标

主要结局

Elbow extension angle in degrees in Upper limb neurodynamic test (ULNT 1) , Hand Sensibility Measures includes Vibration Threshold in Volts,

时间窗: Baseline

Two Point Discrimination Score 0- 10, Monofilament Testing Score 0-21 and velocity (m/s ), Amplitude (m/s) in Sensory nerve conduction study

时间窗: Baseline

次要结局

  • Not Applicable(Not Applicable)

研究者

发起方
Harshika Raut
申办方类型
Other [Self- sponsored]
责任方
Principal Investigator
主要研究者

Harshika Raut

Manipal College of Health Professions, Manipal Academy of Higher Education

研究点 (1)

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