NCT02873507撤回不适用
Pilot Study for the Prediction of Donor Liver Adipose Content by Magnetic Resonance Imaging
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 主要终点
- Percent Hepatic Steatosis of a Donor Liver Prior to Transplantation
研究概览
简要总结
A pilot prospective cohort study assessing the clinical utility of MRI evaluation of graft steatosis prior to transplantation will be conducted. An MRI of the donor liver within the transport cooler will be obtained on its way to the operating room.
详细描述
The images from MRI will be analyzed to obtain information of fat content in all eight segments of the liver. Demographic, intra-operative, and post-operative patient data will be collected for each imaged graft.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who are scheduled to orthoptic liver transplant
排除标准
- •Patient's who do not agree to sign consent
结局指标
主要结局
Percent Hepatic Steatosis of a Donor Liver Prior to Transplantation
时间窗: Measured immediately prior to liver transplant
Amount of fat measured in the donor liver prior to transplant surgery using MRI scan
次要结局
- Comparison of steatosis percentages provided by biopsy to MRI results(Baseline)
- Length of hospitalization of transplant recipient(Days to hospital discharge, approximately 2 weeks)
- Mortality of liver transplant recipient at 1 year post transplantation(1 year)
研究者
Bret Alvis
Assistant Professor
Vanderbilt University Medical Center
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