Effects of a Program of Deep Inspiration Combined to Expiratory Positive Airway in Quality of Life and Heart Rate Variability
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 14
- 试验地点
- 1
- 主要终点
- The effect of deep inspiration and positive expiratory airway pressure in quality of life in adults with severe asthma
研究概览
简要总结
The purpose of this study is to determine the effects of a deep inspiration combined to expiratory positive airway pressure protocol on respiratory function, quality of life, exercise tolerance and heart rate variability in adults with severe asthma.
详细描述
Asthma is associated with high morbidity and significant mortality. This disease has functional impact on activities of daily living (ADLs) and according to some studies in the United States and Europe, the percentage of asthmatics who have significant restrictions in their ADLs is quite significant. Asthma is characterized as a major public health problem, not only in Brazil but worldwide. Currently there are few studies reporting the effects of a domiciliary program of deep inspiration associated with positive expiratory pressure in the airways of asthmatics. This study aims to analyze the benefits of this program on lung function, quality of life and response to exercise.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age between 20 and 80
- •Severe asthma
排除标准
- •Disagreement with consent form
- •Other respiratory disease
- •Acute severe asthma
- •Pregnancy or breastfeeding
- •Current smoking
- •Lack of capable of conducting the study visits
研究组 & 干预措施
Deep inspiration and expiratory positive airway pressure
The protocol of deep inspiration combined to expiratory positive airway pressure will be applied in asthmatic subjects.
干预措施: Deep inspiration and positive expiratory airway pressure (Other)
Control
结局指标
主要结局
The effect of deep inspiration and positive expiratory airway pressure in quality of life in adults with severe asthma
时间窗: Change in quality of life at 5 week
The quality of life will be measure by a specific questionnaire for this population 5 weeks apart.
次要结局
- The effect of deep inspiration and positive expiratory airway pressure in respiratory function in adults with severe asthma.(Change in respiratory function at 5 week)
- The effect of deep inspiration and positive expiratory airway pressure in exercise tolerance in adults with severe asthma.(Change in exercise tolerance at 5 week)
- The effect of deep inspiration and positive expiratory airway pressure in heart rate variability in adults with severe asthma.(Change in heart rate variability at 5 week)
研究者
Pedro Dal Lago
Professor
Federal University of Health Science of Porto Alegre