A Comparative Study on the Efficacy of Blue Light Emitting Diodes Therapy Versus Targeted Narrow Band UVB in Stable Non-segmental Vitiligo Patients.
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Assess the degree of improvement in vitiligo pigmentation using VASI scores before and after treatment.
研究概览
简要总结
A comparative study on the efficacy of blue light emitting diodes therapy versus targeted Narrow band UVB in stable non-segmental vitiligo patients.
详细描述
A comparative study on the efficacy of blue light emitting diodes therapy versus targeted Narrow band UVB in stable non-segmental vitiligo patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All age group.
- •Both genders.
- •Subjects with stable non-segmental vitiligo (≥2 patches) acral or non-acral patches of diameter ≤ 2cm.
排除标准
- •Prior treatment with laser therapies for at least 3 months
- •Recent exfoliation procedures.
- •Recent surgical procedures.
- •Poor skin conditions including keloids.
- •Hypersensitivity to light ( visible and near-infrared).
- •Medications that make users more sensitive to light.
- •Anticoagulant and immunosuppressive treatments.
- •Gestations or breastfeeding.
- •A personal or family history of skin cancer.
- •Unstable vitiligo (older lesions have not progressed for the last 1 years and lack of Koebner phenomena ).
研究组 & 干预措施
patients will receive NB-UVB phototherapy sessions on a Randomly selected patch
patients will receive NB-UVB phototherapy sessions on a Randomly selected patch
干预措施: Narrow Band UVB Treatment (Device)
Patients will receive blue light emitting diodes phototherapy on a randomly selected patch
Patients will receive blue light emitting diodes phototherapy on a randomly selected patch
干预措施: blue light emitting diode (Device)
结局指标
主要结局
Assess the degree of improvement in vitiligo pigmentation using VASI scores before and after treatment.
时间窗: 48 weeks
Assess the degree of improvement in vitiligo pigmentation using VASI scores before and after treatment.
次要结局
未报告次要终点
研究者
Nahla Maher Mahmoud Mahran
Lecturer of Dermatology
Cairo University