Randomized multicenter trial for investigating effect of neurofeedback with gait imagery training on Parkinson's disease patients

Mihara Masahito0 个研究点目标入组 50 人开始时间: 2022年6月8日最近更新: 2024年1月22日

适应症

试验速览

暂无简介。

•1) patients who had written informed consent
•2) age older than 39 year old
•3) PD patients with diagnosis of clinically probable or clinically established PD in MDS criteria
•4) Patients with Hoehn-Yahr stage 2 to 4
•5) Patients who can walk 10 m safely with or without aid
•6) Patients whose anti-Parkinsonian drug is not changed for at least 2 months at the time of registration
•7) Patients who can understand the verbal order and perform task

•1) moderate to severe dmentia with MMSE score< 22
•2) Patients with cortical lesion covering media premotor area including the supplementary motor area
•3) Patients with history of symptomatic stroke or Epilepsy
•4) patients with severe Anterior Cerebral Artery stenosis (>90%)
•5) Patients wiht history of neurosurgical operation including Deep brain stimulation and trans-arterialaneurysm coil embolization)
•6) Patients unstable in vital signs
•7) Patients with corrected binocular visual acuity less than 1/20
•8) Patients with scalp lesion which needed treatment
•9) Women with Pregnancy, lactating, or suspected pregnancy
•10) Patients who is unable to perform brain MRI scannning
•11) Patients with past or current history of clinically established psychological illness (needs wnti-psychotic drugs).
•12) Patients have experienced experimental brain stimulation intervention (including repetitive trans
•cranial magnetic stimuration or transcranial direct/alternative current stimulation) within 6 months prior to the enrollment.
•13) Patients with severe, unpredicable wearing-off which disturb stable evaluation in each visit
•14) Patients with muscloskeltal complication which affect gait performance
•15) Patients assumed to be inadequate fore enrollment by their attending physician

发起方

Mihara Masahito