Evaluation of clinical efficacy of autologous plasma therapy for the patients with recalcitrant atopic dermatitis and identification of plasma fraction mediating therapeutic efficacy

Ajou University Hospital0 个研究点目标入组 36 人开始时间: 待定最近更新: 2019年3月11日

适应症

试验速览

暂无简介。

•36 patients with recalcitrant AD whose clinical conditions had not been effectively controlled by current standard medical therapies (topical moisturizers, topical corticosteroids, topical calcineurin inhibitors, and oral antihistamines) for more than 6 months who visited out-patient clinic of the university hospital will be recruited. Written informed consent on this study will be received from all the participating patients and the patients will be divided into 2 experimental groups (12 patients in autologous plasma injection group, 12 patients in high molecular plasma protein injection group) and 1 control group (12 patients in saline injection group) for this study.

•1) Patients under the age of 16
•2) Patients who are unable to agree on their own (emergency patients, patients with mental disability, patients with limited capacity to consent due to stroke or delirium caused by diabetes)
•3) Pregnancy or planned pregnancy within 1 year
•4) Skin condition not appropriate for blood sampling and transfusion
•5) Patients with contraindication for blood transfusion

发起方

Ajou University Hospital