Efficacy of ketamine on acute suicidality, a multicenter double blind randomized placebo-controlled trial (Ketamine Trial Amsterdam, KETA) - Ketamine Trial Amsterdam (KETA)

Academisch Medisch Centrum0 个研究点目标入组 156 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

暂无简介。

•Acute suicidality: suicidal thoughts and/or behaviour have increased within the last 24 hours.
•A Beck Scale for Suicide Ideation (BSSI)-score of 7 or above
•Subjects are in the age of 18-70

•-Earlier participation in this study
•-Psychosis
•-A diagnosis of schizophrenia or another psychotic disorder
•-A history of PCP- or ketamine addiction
•-Being under influence of GHB (Substance abuse in the (recent) history is not an exclusion criterion per se (with the exception of GHB and a high blood alcohol concentration, and intoxications leading to medical unstable conditions)
•-A blood alcohol concentration (BAC)of >0.05%
•-A clinically significant and unstable infectious, immunological, cardiovascular, gastro-intestinal, pulmonal, renal, hepatic, endocrine or haematological disorder, a myocardial infarction, miction problems or a complex surgical problem that needs immediate attention
•-A known hypersensitivity for ketamine
•-Concomitant use of a MAO-inhibitor
•-Severe nose congestion or nasal polyps
•-Pregnancy or giving breastfeeding
•-Women using unreliable contraception
•-Being unable to answer the questionnaires
•-Legal incompetency
•-No informed consent

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