NCT00430911已完成3 期
Radiotherapy for Malignant Astrocytomas in the Elderly
适应症
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 试验地点
- 2
- 主要终点
- Survival
研究概览
简要总结
A randomized trial comparing radiotherapy with supportive care in patients aged 70 years or older with newly diagnosed, histologically confirmed anaplastic astrocytoma or glioblastoma, and a Karnofsky performance status > 70.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 70 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Glioblastoma and anaplastic astrocytoma, supratentorial, histologically confirmed
- •Brain CT scan or MRI within 28 days before surgery
- •Age: 70 years or older
- •Karnofsky performance status, 70 or more.
- •Life expectancy over 12 weeks
- •Informed consent
排除标准
- •Brain radiotherapy
- •Chemotherapy
- •Severe systemic disease
结局指标
主要结局
Survival
次要结局
- Quality of life
- Cognitive functions
- Progression free survival
研究者
研究点 (2)
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