NCT06781892招募中不适用
Strategies for Defibrillation During Out-of-Hospital Cardiac Arrest - A Randomized Clinical Trial
Lars Wiuff Andersen6 个研究点 分布在 1 个国家目标入组 909 人开始时间: 2025年3月15日最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 909
- 试验地点
- 6
- 主要终点
- Survival at 30 days
研究概览
简要总结
The "Strategies for Defibrillation during Out-of-Hospital Cardiac Arrest" (STRAT-DEFI) trial is an investigator-initiated, individually randomized, 3-group clinical trial comparing standard anterior-lateral pad positioning with anterior-posterior positioning and double sequential defibrillation during adult out-of-hospital cardiac arrest.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Out-of-hospital cardiac arrest
- •Age ≥ 18 years
- •≥ 1 manual defibrillation attempt by emergency medical services
- •Shockable rhythm as the last known rhythm
- •Two manual defibrillators present on-site
排除标准
- •Blunt trauma, penetrating trauma, or burn injury suspected to be the cause of the cardiac arrest
- •Prior enrollment in the trial
- •Posterior pad placement not deemed possible by on-site clinician
研究组 & 干预措施
Anterior-lateral pad positioning
Active Comparator
干预措施: Anterior-lateral pad positioning (Other)
Anterior-posterior pad positioning
Experimental
干预措施: Anterior-posterior pad positioning (Other)
Double-sequential defibrillation
Experimental
Anterior-lateral pad positioning combined with anterior-posterior pad positioning for a total of 4 pads and 2 shocks.
干预措施: Double-sequential defibrillation (Other)
结局指标
主要结局
Survival at 30 days
时间窗: 30 days after the cardiac arrest
次要结局
- Survival at 90 days(90 days after the cardiac arrest)
- Favorable neurological outcome at 30 days(30 days after the cardiac arrest)
- Favorable neurological outcome at 90 days(90 days after the cardiac arrest)
研究者
Lars Wiuff Andersen
Professor
Aarhus University Hospital
研究点 (6)
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