The Lymphoma Epidemiology of Outcomes (LEO) Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- Mayo Clinic
- 试验地点
- 8
- 主要终点
- Overall Survival (OS)
研究概览
简要总结
The goal of this infrastructure grant is to establish and maintain a cohort of over 12,000 non-Hodgkin lymphoma (NHL) patients to support broad and cutting-edge research that identifies clinical (including co-morbid diseases), epidemiologic (including lifestyle and other exposures), host genetic, tumor, and treatment factors, as well as the interaction among these factors, on short and long-term outcomes. These efforts will identify new approaches to improve the survival and well-being of NHL patients.
详细描述
Newly diagnosed non-Hodgkin lymphoma (NHL) patients will be recruited from each center participating in the LEO cohort. At time of consent, participants will be asked to completed several questionnaires collecting health history, current medical and quality of life questions. Patients will also provide a baseline blood sample that will processed locally and stored centrally for future research use. Additionally, consent is given for use of excess clinical tumor tissue for research use.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Newly diagnosed non-Hodgkin Lymphoma (NHL), within 183 days of enrollment
- •Patients may have been treated as long as initial NHL diagnosis is within 6 months of enrollment
- •18 years of age or older
排除标准
- •Lymphoma diagnosis greater than 184 days from date of consent
结局指标
主要结局
Overall Survival (OS)
时间窗: Short (<5 years), medium (5-10 years), and long-term (>10 years)
Time from date of diagnosis to date of death
次要结局
- Event Free Survival (EFS)(Short (<5 years), medium (5-10 years), and long-term (>10 years))
- Lymphoma Specific Survival (LSS)(Short (<5 years), medium (5-10 years), and long-term (>10 years))