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临床试验/NCT06828523
NCT06828523招募中不适用

Assessing Perceptual Effects of Interactive Tasks

Penn State University1 个研究点 分布在 1 个国家目标入组 1,300 人开始时间: 2025年10月17日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
1,300
试验地点
1
主要终点
Intelligibility of recorded speech

研究概览

简要总结

In this study, we will evaluate how solo, naive listeners perceive the speech of people with amyotrophic lateral sclerosis (ALS) and age-matched speakers produced across interactive and non-interactive contexts with an unfamiliar, naive interlocutor.

详细描述

Listeners will hear recorded speech of PALS and age-matched speakers and indicate what they heard. Recorded speech consists of vowels and consonants produced in non-interactive and interactive tasks. The perceptual judgements will be compared to see whether interactive contexts have similar perceptual effects across the two groups.

Plans for Assignment - This is a single group study in which all participants will engage in the same tasks.

Delivery of Intervention: Solo listeners will participate in this study in a remote, asynchronous format. They will be recruited using the online participant recruitment platform Prolific © and will use their own laptop/computer and headphones.

Adequacy of Sample size: We will use n = 1300 listeners to achieve 80% power at alpha of .05 to detect between group differences with the assumption of medium effect sizes (Cohen's f = 0.3).

Adequacy of Analyses: The proposed statistical analyses (Generalized mixed effects regressions) are standard and will be used to analyze the effect of the intervention on the outcome measures described below.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •passing the remote hearing screening
  • •having no known speech, language or neurological disorders per self-report
  • •being a native monolingual speaker of American English
  • •having no experience communicating with people with dysarthria
  • •being between the ages of 18 and 65.

排除标准

  • •None - if volunteer meets the inclusion criteria, then they will be enrolled

研究组 & 干预措施

Listener Perception of Speech Produced in Different Task Settings

Experimental

Listeners will hear recorded speech of PALS and age-matched speakers produced within interactive and non-interactive contexts and indicate what they heard.

干预措施: Listener judgements of speech produced in different tasks (Behavioral)

结局指标

主要结局

Intelligibility of recorded speech

时间窗: one 20 minute session

Perceptual judgments will be provided by solo, naïve listeners who did not participate in the interactions. Listeners will hear recorded speech of PALS and age-matched speakers recorded across the different tasks and indicate what they heard. The score will be expressed in percent. The possible range is between 0-100%. The higher scores mean a better outcome.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ji Min Lee, Ph.D.

Associate Professor

Penn State University

研究点 (1)

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