NCT00421265Unknown不适用
Prospective Cohort Study of Active Surveillance for Prostate Cancer With Indolent Linical Features
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 150
- 试验地点
- 1
研究概览
简要总结
In patients with prostate cancer with indolent features, disease progrssion may be very slow and in many cases will never become clinically evident during the patient's lifetime. Active surveillance is a continuous process of monitoring disease characteristcs aiming to avoid the morbidity of active therapy in patients with stabe indolent parameters, while offering early detection of disease activity in others who will need active therapy to control their disease. We hypothesize that active surveillance will permit the avoidance of therapy related morbidity in the majority of appropriate patients and will be associated with maintaining their quality of life.
研究设计
- 研究类型
- Observational
- 观察模型
- Defined Population
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 80 Years(Older Adult)
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Men 65 years of age or older who were diagnosed with prostate cancer in the past 3 month prior to inclusion
- •Gleason's score of 6 or less.
- •Clinical T1C per digital rectal exam.
- •Pre biopsy PSA serum level of 6.0ng/ml or less.
- •The presence of cancer in a single biopsy core of at least 8 taken.
- •The presence of cancer in no more than 10% of the length of the core involved.
- •Patient's consent to engage in active surveillance after being informed of the benefits and potential risks of this approach as well as of alternative lines of therapy.
- •Israeli residence with the readiness to be available for the followup schedule.
排除标准
- •Patients who do not meet the above eligibility criteria
研究者
研究点 (1)
Loading locations...
相似试验
已完成
2 期
Active Surveillance With or Without Apalutamide Treatment in Low Risk Prostate CancerLow Risk Prostate CancerNCT03088124Institut Paoli-Calmettes93
终止
不适用
Observation or Radical Treatment in Patients With Prostate CancerProstate CancerNCT00499174NCIC Clinical Trials Group180
招募中
2 期
Active surveillance for early prostate cancer: international study (PRIAS-JAPAN)Prostate cancerJPRN-UMIN000002874Kagawa university1,400
终止
不适用
Active Control of Prostatic Cancer With Criteria of LatenceProstate CancerNCT00921258Clinique Mutualiste Chirurgicale de la Loire100
暂停
不适用
Non-Invasive Biomarkers in Prostate Cancer Disease ManagementProstate CancerNCT06144619H. Lee Moffitt Cancer Center and Research Institute500
