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临床试验/NCT04112004
NCT04112004已完成不适用

Effect of Perioperative Delta Sodium on Outcomes in Liver Transplant Recipients

Institute of Liver and Biliary Sciences, India1 个研究点 分布在 1 个国家目标入组 342 人开始时间: 2011年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
342
试验地点
1
主要终点
post transplant mortality

研究概览

简要总结

We analyzed the association of delta sodium levels with their effect on post liver transplant outcomes in consecutive patients undergoing liver transplantation. Records were analyzed for electrolytes and outcome measures, and data was analyzed.

详细描述

Preoperative hyponatremia was identified in patients. The mean change in sodium in hyponatremic patients was compared with inpatients with normal sodium levels. The impact of the delta sodium levels with short-term outcomes, such as duration of intubation, intensive care unit length of stay were analyzed with univariate and multivariate logistic regression analyses.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All liver transplant recipients between Jan 2011 to Jan 2017
  • Records available

排除标准

  • Acute fulminant liver failure
  • All patients less than 18 years
  • Re operated cases
  • Pregnant patients

结局指标

主要结局

post transplant mortality

时间窗: 1 month

post transplant mortality after liver transplantation

change in serum sodium in liver transplant recipients

时间窗: 1 day

difference between baseline and postoperative sodium in liver transplant recipients

次要结局

  • post operative neurological complications(1 month)
  • Duration of ICU stay(1 month)
  • duration of mechanical ventilation(1 month)
  • Duration of hospital stay(1 month)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Karthik Ponnappan T

Consultant

Institute of Liver and Biliary Sciences, India

研究点 (1)

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