Effect of Perioperative Delta Sodium on Outcomes in Liver Transplant Recipients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 342
- 试验地点
- 1
- 主要终点
- post transplant mortality
研究概览
简要总结
We analyzed the association of delta sodium levels with their effect on post liver transplant outcomes in consecutive patients undergoing liver transplantation. Records were analyzed for electrolytes and outcome measures, and data was analyzed.
详细描述
Preoperative hyponatremia was identified in patients. The mean change in sodium in hyponatremic patients was compared with inpatients with normal sodium levels. The impact of the delta sodium levels with short-term outcomes, such as duration of intubation, intensive care unit length of stay were analyzed with univariate and multivariate logistic regression analyses.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All liver transplant recipients between Jan 2011 to Jan 2017
- •Records available
排除标准
- •Acute fulminant liver failure
- •All patients less than 18 years
- •Re operated cases
- •Pregnant patients
结局指标
主要结局
post transplant mortality
时间窗: 1 month
post transplant mortality after liver transplantation
change in serum sodium in liver transplant recipients
时间窗: 1 day
difference between baseline and postoperative sodium in liver transplant recipients
次要结局
- post operative neurological complications(1 month)
- Duration of ICU stay(1 month)
- duration of mechanical ventilation(1 month)
- Duration of hospital stay(1 month)
研究者
Karthik Ponnappan T
Consultant
Institute of Liver and Biliary Sciences, India
