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临床试验/NCT06701773
NCT06701773已完成不适用

Computational Fluid Dynamics Predicting Intraprosthetic Thrombus Formation and Progression Following Endovascular Aortic Repair: a Two-center Retrospective Study

Xiangya Hospital of Central South University0 个研究点目标入组 72 人开始时间: 2014年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
72
主要终点
Degree of intraprosthetic thrombus in limb graft

研究概览

简要总结

Intraprosthetic thrombus (IPT) formation and its progression to limb graft occlusion (LGO) are significant complications following endovascular aneurysm repair (EVAR). Morphological metrics based on preoperative CTA have limited predictive value for these complications. This study aims to assess the potential of computational fluid dynamics (CFD) in predicting IPT formation and its progression to LGO after EVAR.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Aged 18 and above;
  • Patients undergone endovascular aneurysm repair;
  • Signed informed consent forms, willing to receive treatments.

排除标准

  • inflammatory aortic aneurysm;
  • patients diagnosed with connective tissue diseases;
  • patients diagnosed with atrial fibrillation;
  • patients lacking post-operative CTA;
  • Patients who are participating in other clinical projects;
  • Patients are not suitable to participate in this study.

结局指标

主要结局

Degree of intraprosthetic thrombus in limb graft

时间窗: From January 2014 to June 2024

Evaluate the area of thrombus occupying the lumen using postoperative CTA

次要结局

  • Disease-related complications(From January 2014 to June 2024)

研究者

发起方
Xiangya Hospital of Central South University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Wei Wang

Professor

Xiangya Hospital of Central South University

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