Comparison Of Efficacy Of Hydrocortisone And Methyl Prednisolone In Acute Severe Asthma
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 60
- 试验地点
- 4
- 主要终点
- Spirometry
研究概览
简要总结
COMPARISON OF EFFICACY OF HYDROCORTISONE AND METHYLPREDNISOLONE IN ACUTE SEVERE ASTHMA
In this study Investigator will compare the efficacy of hydrocortisone and methyl prednisolone in acute severe asthma that will lead to final result and beneficial effects that will help in early resoloution of symptoms and help in preventing recurrence
详细描述
investigator will compare the efficacy of hydrocortisone v/s methylprednisolone in management of patients presented with acute severe asthma in emergency.
A local study was conducted in 2009, after that there is a big research gap exists at national level although international literature is available on the same but it can not be generalized to our population due to socio, geographic and economic differences so there is dire need to conduct this study this gives a strong rationale to implement in our settings
研究设计
- 研究类型
- Observational
- 观察模型
- Ecologic Or Community
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Either Gender (18 to 50 years old)
- •Patient presenting to emergency department with acute severe asthma
排除标准
- •Patients with critical illness or pregnant females. .Patient treated other than hydrocortisone and methylprednisolone. .Patients not willing to participate in study.
- •Life threatening asthma
- •Near fatal asthm
研究组 & 干预措施
METHYLPREDNISOLONE
Group B will be treated with methylprednisolone 125 mg stat
干预措施: Methylprednisolone, (Drug)
结局指标
主要结局
Spirometry
时间窗: 24 hours
Above will be check on arrival of patient to Emergency and post Managment
Blood pressures
时间窗: 24 hours
Vital signs at initial presentation and post managment will be recorded Blood pressure in mm HG will be recorded
Heart rate
时间窗: 24 hours
Heart rate beats/min will be checked
PEAK EXPIRATORY FLOW RATE
时间窗: 24 hours
it wil be checked on arrival and post managment in Peak Expiratory Flow rate (force expiratory volume in 1 second and force vital capacity )will be examined
Respiratory rate
时间窗: 24 hours
Respiratory rate at arrival and post managment will be considered Respiratory rate in Breaths/min
次要结局
未报告次要终点
研究者
Inayat Ur Rehman
Principal Investigator
University of Karachi