Exercise-induced Steroid Changes in Active Surveillance for Prostate Cancer
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 49
- 试验地点
- 1
- 主要终点
- Protocol Completion Rate
研究概览
简要总结
The purpose of this research study is to understand how a short session of a home-based bodyweight high-intensity interval training (HIIT) affects steroid hormone levels in men on active surveillance for low-grade prostate cancer.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Males 18 to 80 years old
- •Diagnosis of localized prostate cancer
- •Currently under active surveillance
- •Ability to perform moderate-to-high intensity physical activity as demonstrated by self-assessment using the Physical Activity Readiness Questionnaire (PAR-Q+)
- •Able to independently perform activities of daily living, without limitations in mobility
- •Ability to read, write, speak, and understand English
- •Able and willing to sign consent and comply with study requirements
排除标准
- •Males currently receiving treatment for prostate cancer
- •Diagnosis of metastatic prostate cancer
- •Individuals with medical conditions contraindicating exercise
- •Uncontrolled cardiovascular or circulatory diseases, hypertension, and diabetes, as determined by the study doctor or treating physician
- •Ongoing use of medications affecting steroid metabolism
- •Unable to sign consent and/or comply with study requirements
研究组 & 干预措施
Home-Based High Intensity Interval Training (HIIT) Exercise Session + Saliva Collection
Participants will complete a single supervised, online high intensity interval training (HIIT) exercise session with six bouts of 1-minute exercises performed at a moderate-to-high intensity lasting approximately 20 minutes. Saliva samples will be collected immediately prior to exercise, immediately following exercise, and 15 minutes post-exercise.
干预措施: High-Intensity Interval Training (HIIT) Exercise (Behavioral)
结局指标
主要结局
Protocol Completion Rate
时间窗: From enrollment through completion of all study procedures (up to Day 1)
Protocol Completion Rate is defined as the proportion of enrolled participants who complete both the supervised home-based HIIT exercise session and return all scheduled saliva samples to the laboratory.
次要结局
- Acceptability of the Exercise and Saliva Collection Protocol(Immediately after protocol completion (Day 1))
研究者
Nima Sharifi
Professor and Scientific Director of the Desai Sethi Urology Institute
University of Miami