Combined Effect of Repetitive Transcranial Magnetic Stimulation and Task-Specific Trunk Control Training on Postural Stability in Individuals with Parkinson’s Disease.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Movement Disorder Society-Unified Parkinson’s Disease Rating Scale (MDS-UPDRS)- Motor Part -III
研究概览
简要总结
This study was a Randomized Controlled Trial (RCT) investigating the combined effect of Repetitive Transcranial Magnetic Stimulation (rTMS) and Task-specific Trunk Control Training on postural stability in individuals with Parkinson’s Disease (PD). A total of 16 participants met the inclusion criteria and completed the study.
The study was conducted at multiple physiotherapy and neurorehabilitation centers in Patiala, India. Ethical approval was obtained, and informed consent was secured from all participants.
Participants were randomly divided into two groups:
Group A: Received rTMS, Task-specific Trunk Control Training, and Conventional Physiotherapy.
Group B: Received Sham rTMS, Task-specific Trunk Control Training, and Conventional Physiotherapy.
Assessments were conducted at baseline, Day 7, and Day 15 using:
MDS-UPDRS-III (Movement Disorder Society-Unified Parkinson’s Disease Rating Scale - motor part
m-CTSIB (Modified Clinical Test of Sensory Interaction in Balance)
PDQL (Parkinson’s Disease Quality of Life Scale)
The intervention lasted 3 weeks (5 days per week), with progressive exercises focusing on balance, trunk control, and functional mobility. Post-intervention data were analyzed to evaluate improvements in motor function, balance, and quality of life.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 40.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- All
入选标准
- •Individuals who will be willing to participate and able to give informed consent.
- •Individuals diagnosed with Parkinson’s disease according to ICF domains.
- •Individuals with Hoehn & Yahr stage between 2 and
- •Individuals with a MMSE score more than
- •Individuals with balance deficits (mPOMA score less than 23).
排除标准
- •Individuals with any pre-existing neurological disease other than PD.
- •Individuals with any magnetic-sensitive metallic implants close to the stimulation site.
- •Any systematic illness.
- •Presence of any orthopedic disease, visual problems, or vestibular disorders that could affect balance.
- •Surgery in lower limb and spine.
- •Non-cooperative individuals.
结局指标
主要结局
Movement Disorder Society-Unified Parkinson’s Disease Rating Scale (MDS-UPDRS)- Motor Part -III
时间窗: At baseline, day 7, day 15
次要结局
- Quality of life-PDQL (Parkinson’s disease quality of life)(At Baseline, day 7, day 15)
- Modified Clinical Test of Sensory Interaction in Balance (m-CTSIB)(At baseline, Day 7, Day 15)